Evidence map›Paper›PMID 41537033›Full record

ArticleMalaysian orthopaedic journal2025

Fast-setting Bone Cement in Total Knee Arthroplasty: A Case Series Looking at Safety and Short-term Radiological Outcomes.

P D'sa, S Mercer, S Ghosh, B K Thomas, L Atkinson, S Bajada, R Williams

Abstract read
In one paragraph

Article in Malaysian orthopaedic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

P D'saDepartment of Trauma and Orthopaedics, Glangwili General Hospital (GGH), Carmarthen, United Kingdom.
S MercerDepartment of Trauma and Orthopaedics, Glangwili General Hospital (GGH), Carmarthen, United Kingdom.
S GhoshDepartment of Trauma and Orthopaedics, Glangwili General Hospital (GGH), Carmarthen, United Kingdom.
B K ThomasDepartment of Trauma and Orthopaedics, Glangwili General Hospital (GGH), Carmarthen, United Kingdom.
L AtkinsonDepartment of Trauma and Orthopaedics, Glangwili General Hospital (GGH), Carmarthen, United Kingdom.
S BajadaDepartment of Trauma and Orthopaedics, Glangwili General Hospital (GGH), Carmarthen, United Kingdom.
R WilliamsDepartment of Trauma and Orthopaedics, Glangwili General Hospital (GGH), Carmarthen, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fast-setting high viscosity cement was introduced in the last decade, offering arthroplasty surgeons the benefit of shortened setting time. This could reduce the operating time, which may reduce the risk of infection and improve theatre efficiency. PALACOS® Fast R+G high viscosity cement has an average setting time of less than 6 minutes (30% faster than regular PALACOS® R+G) due to the lack of a waiting phase. The aim of this study was to investigate the safety of total knee arthroplasty performed using this fast-setting, high viscosity cement and short-term radiological outcomes. Material and Methods: This single surgeon case series looked at 344 primary TKAs performed using PALACOS® fast R+G cement from January 2016 to March 2020. Data were collected on patient demographics, perioperative events, and complications. Radiographs taken immediately post-operatively and at the one-year follow-up were analysed using the Knee Society Roentgenographic Evaluation and Scoring System (KSRESS). Results: This case series included 313 consecutive patients (31 bilateral) with a mean age of 70 years (range 44-93). A total of 237 patients (76%, 262 TKA patients) had a minimum one-year follow-up. No adverse events were noted perioperatively; ten patients had superficial wound issues and were managed successfully with wound care and/or oral antibiotics. Six (1.7%) patients underwent re-operation in the study period. These included one DAIR, one staged revision for deep infection, two revisions for instability, one manipulation under anaesthetic for stiffness, and one patella internal fixation for fracture. The mean combined valgus angle for the prosthesis was 183.1° (range 177.7° to 187.8°), indicating adequate alignment. At one-year follow-up, no radiographs demonstrated any new loosening or worsening of any previously noted radiolucent lines. Conclusion: This study reports the largest case series that looks at the use of fast-setting bone cement in primary TKA. It demonstrates good safety, as evidenced by a low re-operation rate, deep infection rate, and no adverse events during implantation. Fast-setting cement offers the promise of improving theatre efficiency and decreasing total running costs. Further studies are needed to provide data on improved theatre efficiency, cost savings and the longevity of implanted knees utilising this cement.

Indexed as

fast-setting bone cementKSRESS scorePALACOS® fast R+Gsafetytotal knee arthroplasty

Identifiers

PMID41537033
PMCPMC12798085

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