Evidence map›Paper›PMID 41536996›Full record

ArticleiScience2026

Locomotion selectively enhances visual speed encoding in mouse medial higher visual areas.

Edward A B Horrocks, Aman B Saleem

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edward A B HorrocksInstitute of Behavioural Neuroscience, University College London, London WC1V 0AP, UK.
Aman B SaleemInstitute of Behavioural Neuroscience, University College London, London WC1V 0AP, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian visual systems are comprised of multiple brain areas with distinct functional roles. While functional specializations have been proposed in the mouse based on visual feature encoding, the extent to which these specializations are contingent on ongoing behavior is unknown. To address this, we analyzed the neural encoding of visual motion stimuli by thousands of neurons recorded in six cortical and two thalamic visual areas while mice were stationary or locomoting. We found locomotion selectively enhanced visual speed encoding in medial higher visual cortical areas, indicating that these areas may be specialized for processing visual motion during locomotion. By contrast, the encoding of drifting gratings direction was enhanced non-selectively across the mouse visual cortex during locomotion. Our results reveal how a complex interplay of sensory input and ongoing behavior differentially shapes the efficacy of sensory processing in mouse higher visual areas, supporting context-dependent functional roles.

Indexed as

Health sciences

Identifiers

PMID41536996
PMCPMC12796763

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.