ReviewJournal of International Society of Preventive & Community Dentistry
Impact of Hyaluronic Acid Around Dental Implants: A Systematic Review.
Review in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: Hyaluronic acid (HA), a naturally occurring glycosaminoglycan, has gained attention in dental implantology due to its bioactive, anti-inflammatory, and wound-healing properties. This systematic review evaluates the current evidence regarding the application and efficacy of HA around dental implants, focusing on its impact on peri-implant tissue health, osseointegration, and prevention of peri-implant diseases. Materials and Methods: A comprehensive search was conducted across PubMed, Scopus, Embase, Cochrane Library, Google Scholar, and Web of Science databases for studies published from 2016 to 2024. Inclusion criteria: Encompassed human studies, animal studies, and Results: It is demonstrated that HA application positively influences soft tissue healing, reduces inflammation, and may support early osseointegration. Despite promising findings, heterogeneity in HA formulations, application protocols, and follow-up durations limits the ability to draw definitive conclusions. Further long-term, standardized clinical trials are needed to validate its routine use in implant dentistry. Conclusion: This review highlights HA's potential as a valuable adjunct in implant therapy, especially for enhancing peri-implant tissue health and managing early peri-implant disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.