Evidence map›Paper›PMID 41536681›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025

[Relationship Between Neonatal Outcomes and Changes in Serum Platelet-Activating Factor, Fibulin-3, and Umbilical Artery Blood Flow During Late Pregnancy in Pregnant Women With Gestational Hypertension].

Yingmei Sun, Hongli Zhang, Li Sun

Abstract readEnglish Abstract
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Analysis of Maternal Pregnancy Characteristics and Adverse Neonatal Birth Outcomes at a Single Center From 2017 to 2022].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yingmei Sun( 230000) Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230000, China.ORCID 0009-0005-0579-6823
Hongli Zhang( 230000) Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230000, China.
Li Sun( 230000) Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To analyze the relationship between changes in platelet-activating factor (PAF), fibulin-3, and umbilical artery blood flow during late pregnancy in pregnant women with gestational hypertension (GH) and neonatal outcomes. Methods: The data of 420 pregnant women with GH who underwent regular prenatal examinations and who delivered at our hospital between January 2020 and December 2024 were collected. The pregnant women were divided into a good outcome group ( Results: Statistically significant differences were observed between the poor outcome group and the good outcome group in terms of age, pre-pregnancy body mass index (BMI), severe GH, PAF, fibulin-3, and umbilical artery blood flow parameters (ratio of peak systolic velocity to end-diastolic maximum velocity [S/D], pulsatility index [PI], and resistance index [RI]) ( Conclusion: Changes in serum PAF, fibulin-3, and umbilical artery blood flow parameters in pregnant women with GH are associated with neonatal outcomes. Increased fibulin-3 is a protective factor, whereas decreased serum PAF level and decreased umbilical artery S/D, PI, and RI are risk factors. The prediction model based on fibulin-3, PAF, S/D, PI, and RI in this study demonstrates high clinical applicability and potential for broader use.

Indexed as

Extracellular Matrix ProteinsHypertension, Pregnancy-InducedPlatelet Activating FactorPregnancy OutcomeUmbilical ArteriesAdultFemaleHumansInfant, NewbornLogistic ModelsPregnancyPregnancy Trimester, ThirdRisk FactorsEFEMP2 protein, humanExtracellular Matrix ProteinsPlatelet Activating FactorFibulin-3Gestational hypertensionLate pregnancyNeonatal outcomesPlatelet-activating factor

Identifiers

PMID41536681
PMCPMC12796900

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.