ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025
[Correlation of Serum Neuron-Specific Enolase, Angiopoietin-1, and Angiopoietin-Like Protein-3 With Disease Severity and Their Prognostic Value in Patients With Cerebral Infarction].
Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the association between the disease severity and prognosis of cerebral infarction patients and serum levels of neuron-specific enolase (NSE), angiopoietin-1 (Ang-1), and angiopoietin-like protein-3 (ANGPTL3). Methods: A total of 510 patients with cerebral infarction admitted to the Department of Neurology, the First People's Hospital of Jiujiang City, Jiangxi Province between February 2022 and May 2024 were enrolled. According to their disease severity, the patients were divided into a mild group ( Results: Serum NSE and ANGPTL3 levels in the severe group were significantly higher than those in the moderate and mild groups, whereas the serum Ang-1 levels in the severe group were significantly lower than those in the moderate and mild groups (all Conclusion: The severity and prognosis of cerebral infarction patients are strongly correlated with high serum NSE and ANGPTL3 levels and low Ang-1 levels. Monitoring changes in these 3 biomarkers may inform clinical treatment of patients with cerebral infarction.
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