Evidence map›Paper›PMID 41536651›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025

[Performance of Plasma Multigene Methylation Testing in Early Diagnosis of Colorectal Cancer].

Ningning Sheng, Yi Guo, Xiancun Hou, Yiyu Wang, Yinhai Xu

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ningning Sheng（ 221000） Department of Nuclear Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.ORCID 0009-0002-6026-5062
Yi Guo（ 221000） Department of Nuclear Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Xiancun Hou（ 221000） Department of Nuclear Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Yiyu Wang（ 221000） Department of Nuclear Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Yinhai Xu（ 221000） Department of Nuclear Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.ORCID 0009-0002-6026-5062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the performance of a predictive model based on plasma multigene methylation testing in the early diagnosis of colorectal cancer (CRC). Methods: A total of 688 patients with suspected CRC who underwent diagnostic examination at the Affiliated Hospital of Xuzhou Medical University between July 2022 and June 2024 were enrolled. The plasma methylation status of 5 genes, including Results: Of the 688 patients, 48 had a pathologically confirmed diagnosis of colorectal carcinoma. The diagnostic performance of a single-gene methylation status for CRC was as follows: Conclusion: A diagnostic model based on the methylation levels of the

Indexed as

Colorectal NeoplasmsDNA MethylationEarly Detection of CancerAdultAgedFemaleHumansIkaros Transcription FactorMaleMiddle AgedProto-Oncogene Proteins c-vavSeptinsTransaminasesBCAT1 protein, humanIkaros Transcription FactorIKZF1 protein, humanProto-Oncogene Proteins c-vavSEPTIN9 protein, humanSeptinsTransaminasesVAV3 protein, humanColorectal cancerDiagnostic modelEarly diagnosisGene methylationPlasma

Identifiers

PMID41536651
PMCPMC12796887

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.