Evidence map›Paper›PMID 41536613›Full record

ArticleOpen forum infectious diseases2026

Botulism Sequelae: A Systematic Review.

Mark Kosenko, Veronika Rogozhina, Tamerlan Erdniev, Armen K Shakaryan, Dmitry Tumurov, Ekaterina Ligskaya, Svetlana Gadetskaya, Alina Eremeeva, Margarita Andreeva, Maria Pyatnitskaya and 7 more

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In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Mark KosenkoDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0003-2467-466X
Veronika RogozhinaDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia.
Tamerlan ErdnievDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0003-4253-1646
Armen K ShakaryanFederal State Autonomous Scientific Institution "Chumakov Federal Center for Research and Development of Immune-and-Biological Products of the Russian Academy of Sciences" (Institute of Poliomyelitis) (FSASI "Chumakov FSC R&D IBP RAS"), Moscow, Russia.ORCID https://orcid.org/0000-0003-3417-3631
Dmitry TumurovMoscow Research and Clinical Center for Neuropsychiatry, Moscow, Russia.ORCID https://orcid.org/0000-0001-7183-6209
Ekaterina LigskayaDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0009-0006-1262-8518
Svetlana GadetskayaDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia.
Alina EremeevaDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0002-2892-4665
Margarita AndreevaUniversity of British Columbia, Vancouver, Canada.
Maria PyatnitskayaErasmus School of Health Policy & Management, Rotterdam, Netherlands.ORCID https://orcid.org/0009-0007-0180-1167
Ekaterina PazukhinaCentre for Cancer Screening, Prevention and Early Detection, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Alan AsmanovVeltischev Scientific Research Clinical Institute of Pediatrics and Children Surgery, Pirogov Russian National Research Medical University, Moscow, Russia.
Danilo BuonsensoDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0001-8567-2639
Luis Felipe ReyesUnisabana Center for Translational Science, School of Medicine, Universidad de La Sabana, Chia, Colombia.
Timothy R NicholsonInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Alla GuekhtMoscow Research and Clinical Center for Neuropsychiatry, Moscow, Russia.
Daniel MunblitDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia.ORCID https://orcid.org/0000-0001-9652-6856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Botulism is a life-threatening neuroparalytic disease caused by botulinum neurotoxins. While its acute phase has been extensively studied, long-term sequelae following recovery remain insufficiently explored. This systematic review aims to comprehensively assess and synthesize available evidence on post-botulism sequelae to improve understanding and guide future research. Methods: A systematic search was conducted in MEDLINE, EMBASE via Ovid, and Web of Science from inception to 24 June 2024. Eligible studies included observational studies, case series, and case reports describing post-recovery symptoms in individuals diagnosed with foodborne, wound, or infant botulism, excluding iatrogenic cases. The risk of bias was assessed using the Critical Appraisal Skills Programme (CASP) checklists. Results: Out of 340 screened records, 9 studies met inclusion criteria, comprising 2 case-control studies ( Conclusions: This systematic review highlights significant long-term sequelae among botulism survivors, particularly fatigue, respiratory impairment, and psychosocial dysfunction. While recovery trajectories suggest improvement over time, persistent symptoms may impact quality of life. Standardized outcome measures and longitudinal studies are needed to elucidate the burden of post-botulism sequelae further and inform clinical management strategies.

Indexed as

botulismClostridium botulinumpost-infectious sequelaequality of lifesystematic review

Identifiers

PMID41536613
PMCPMC12798721

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.