Evidence map›Paper›PMID 41536571›Full record

ArticleBJUI compass2026

Long-term outcomes after cytoreductive partial nephrectomy for metastatic renal cell carcinoma.

Andrea Lopez Sanmiguel, Yash S Khandwala, Emily A Vertosick, Daniel Barbakoff, Roya Ghavamian, Jonathan A Coleman, Mark Dawidek, Andrew J Vickers, A Ari Hakimi, Paul Russo

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea Lopez SanmiguelUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.ORCID https://orcid.org/0000-0002-8558-8194
Yash S KhandwalaUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.
Emily A VertosickDepartment of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York New York USA.
Daniel BarbakoffUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.
Roya GhavamianUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.
Jonathan A ColemanUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.
Mark DawidekUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.
Andrew J VickersDepartment of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York New York USA.ORCID https://orcid.org/0000-0003-1525-6503
A Ari HakimiUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.
Paul RussoUrology Service, Department of Surgery Memorial Sloan Kettering Cancer Center New York New York USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Objectives: To assess treatment outcomes and evaluate patient selection criteria for cytoreductive partial nephrectomy (CRPN) in a unique cohort of metastatic renal cell carcinoma (mRCC) patients. Methods: A retrospective review of mRCC patients who underwent CRPN between 1995 and 2023 at a single institution was performed. Clinical characteristics, perioperative outcomes, longitudinal imaging reports and overall survival data were analysed. Results: Seventy-three patients with mRCC were included. Forty per cent of patients had prior radical nephrectomy, and 44% had prior metastasectomy. The median tumour size was 4 cm (IQR 2.7, 5.5). Median follow-up among patients who survived was 6.7 years (IQR 3.4, 9.6). Median overall survival was 6.1 years (95% CI 4.6 to 7.8). Complications occurred in 22% of patients within 30 days post-surgery. eGFR stabilized at 3 months after surgery, and no patients required dialysis. Larger tumour size was associated with a higher risk of cancer-specific death (HR 1.19, 95% CI 1.07 to 1.31, Conclusion: CRPN was performed effectively as a component of integrated medical and surgical management for highly selected mRCC patients. Preservation of renal function in patients with a solitary kidney or with an intact contralateral kidney was achieved with acceptable surgical morbidity and oncologic outcomes.

Indexed as

cytoreductive partial nephrectomymetastatic renal cell carcinomapatient selectionrenal functionsurvival analysis

Identifiers

PMID41536571
PMCPMC12795982

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.