ArticleClinical kidney journal2026
Changing microbiology and outcomes of PD-associated peritonitis over four decades.
Article in Clinical kidney journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Predominance of Gram-Negative Pathogens and Treatment Complexity in Peritoneal Dialysis-Associated Peritonitis: A Single-Center Experience.Life (Basel, Switzerland) · 2026Article
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Authors and funding
19 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Peritoneal dialysis (PD)-associated peritonitis remains a major complication affecting patient outcomes and modality survival. This study aims to evaluate temporal trends in pathogen distribution and antibiotic susceptibility over four decades as well as clinical outcomes in PD-associated peritonitis. Methods: We retrospectively analyzed 832 peritonitis cultures of PD patients across four decades from 1979 to 2024 treated at Robert Bosch Hospital, Stuttgart (Germany). For longitudinal comparison of pathogen distribution and antibiotic susceptibility, the study period was divided into four time periods: P1 (1979-1992), P2 (1993-2003), P3 (2004-2014), and P4 (2015-2024). Clinical response and outcomes were assessed in P4. Results: Gram-positive bacteria was the most frequent causative organisms (56%), followed by Gram-negative bacteria (30%) and culture-negative peritonitis (CNP, 13%). Gram-negative peritonitis increased significantly in P4 compared to P1-P3, while coagulase-negative staphylococci (CNS) declined from 31% in P1 to 14% in P4 ( Conclusion: Our findings show temporal changes of microbiological spectrum of PD-associated peritonitis over four decades. Polymicrobial and Gram-negative peritonitis were associated with poorer outcomes, emphasizing the need for ongoing microbiological surveillance and antibiotic stewardship to optimize PD care.
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