A Study Protocol for the X-SIAGA Intervention: A Cluster Randomized Trial to Improve Household Preparedness for Disease X and Outbreaks in Selangor's Indigenous Community.

introductionProactive preparedness strategies are more effective than reactive responses in minimizing the negative impacts of health emergencies, including outbreaks. Despite their potential to enhance community resilience, household preparedness initiatives are limited in Malaysia. The focus is primarily on flood disasters, often overlooking marginalized communities, such as indigenous groups. In Selangor, these communities live near forest edges and depend on the forest for livelihood, increasing their risk of exposure to zoonotic and novel threats such as Disease X. They also face challenges such as socioeconomic status, poor living conditions, healthcare barriers, and societal marginalization, making them particularly vulnerable to severe impacts from outbreaks. This study aims to evaluate the effectiveness of X-SIAGA, a newly developed intervention package, in improving household preparedness for Disease X and potential outbreaks among indigenous communities in Selangor, Malaysia.

methodsThis study will be a two-arm, parallel, single-blinded, cluster-randomized trial using multistage and simple random sampling to evaluate the effectiveness of X-SIAGA. The primary outcome is

resultsAs this is a study protocol, results are not yet available. The study is designed to assess changes in

conclusionThis protocol describes an intervention study that will generate evidence on the effectiveness of X-SIAGA, a novel, culturally tailored, and theory-based intervention designed to improve household preparedness for Disease X and potential outbreaks among indigenous communities in Selangor.