Evidence map›Paper›PMID 41536387›Full record

ArticleCureus2025

Efficacy of Low-Dose Intravenous Immunoglobulin Combined With Immunosuppression Modification in the Treatment of BK Polyomavirus Nephropathy: A Case Series.

Mahesh Eswarappa, Jaish George, Gurudev Kc, Rajshekar R, Gireesh M S, Pooja Prakash Prabhu, Hamsa Reddy, Mohammad Yousuff, Rakesh Veluru

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mahesh EswarappaNephrology, Ramaiah Medical College, Bangalore, IND.
Jaish GeorgeNephrology, Ramaiah Medical College, Bangalore, IND.
Gurudev KcNephrology, Ramaiah Medical College, Bangalore, IND.
Rajshekar RNephrology, Ramaiah Medical College, Bangalore, IND.
Gireesh M SNephrology, Ramaiah Medical College, Bangalore, IND.
Pooja Prakash PrabhuNephrology, Ramaiah Medical College, Bangalore, IND.
Hamsa ReddyNephrology, Ramaiah Medical College, Bangalore, IND.
Mohammad YousuffNephrology, Ramaiah Medical College, Bangalore, IND.
Rakesh VeluruNephrology, Ramaiah Medical College, Bangalore, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New and powerful immunosuppression agents presently available for maintenance immunosuppression and for the treatment of acute and chronic rejection in renal transplantation have led to the emergence of opportunistic infections. One such infection is BK virus nephropathy, leading to graft dysfunction and graft loss. Apart from the reduction and manipulation of immunosuppressive medications, various treatment options such as intravenous immunoglobulin (IVIg), cidofovir, leflunomide, and fluoroquinolones have been tried to treat BK virus nephropathy. We report our experience with low-dose IVIg in six renal transplant recipients with BK polyomavirus nephropathy. We suggest that low-dose IVIg can be a promising treatment option to treat and prevent a decline in renal function and subsequent graft loss.

Indexed as

bk virus nephropathy (bkvn)intravenous immunoglobulin (ivig)renal functionrenal transplant recipientsystemic tacrolimus

Identifiers

PMID41536387
PMCPMC12799318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.