Evidence map›Paper›PMID 41535888›Full record

ReviewMalaria journal2026

Understanding inequities in the malaria landscape of Madagascar: a scoping review of current evidence.

Mamy Jayne Nelly Rajaofera, Wei Liu, Alphonsine Mboty Reziky, Sylvana Tomboanona, Dai Kuang, Qianfeng Xia

Abstract readScoping ReviewReview
In one paragraph

Review in Malaria journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mamy Jayne Nelly Rajaofera *NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, 571199, Hainan, China.
Wei Liu *NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, 571199, Hainan, China.
Alphonsine Mboty RezikyLaboratoire d'Epidémiologie Et de Biostatistique en Santé Des Populations, 401, Mahajanga, Madagascar.
Sylvana TomboanonaEcole Doctorale Ecosystèmes Naturels, Université de Mahajanga, 401, Mahajanga, Madagascar.
Dai KuangNHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, 571199, Hainan, China. kuangdai1989@163.com.
Qianfeng XiaNHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, 571199, Hainan, China. xiaqianfeng@muhn.edu.cn.

Funding

Major Science and Technology Program of Hainan Province ZDKJ202003
6 · The paper itself

Abstract

backgroundMalaria remains a significant public health challenge in Madagascar, affecting vulnerable populations including children under five and pregnant women. Despite global progress in reducing malaria cases and deaths, Madagascar continues to experience a high burden due to inequities in access to prevention, diagnosis, and treatment.

methodsA comprehensive literature review was conducted using major academic databases including PubMed, Web of Science, and Google Scholar. A comprehensive search of literature was conducted in PubMed, Web of Science, Google Scholar, and EBSCOhost. The search focused on studies published between 2015 and 2024, supplemented by online reports. The literature was assessed for quality and relevance to malaria prevention, diagnosis, treatment interventions, and socioeconomic factors in Madagascar.

resultsDisparities in malaria prevention and treatment between urban and rural areas are evident, with remote regions experiencing a higher disease burden. Geographic diversity leads to varied transmission patterns, necessitating region-specific interventions. Rural healthcare infrastructure is insufficient for timely diagnosis and treatment. Key interventions include insecticide-treated nets (ITNs), indoor residual spraying (IRS), and seasonal malaria chemoprevention (SMC). Case management primarily uses Artemisinin-based Combination Therapies (ACTs) and rapid diagnostic tests (RDTs). Social and behavior change communication (SBCC) has improved awareness but faces cultural barriers. SMC has shown promise, though logistical challenges remain. Drug resistance and diagnostic failures, along with socioeconomic inequalities, hinder effective malaria control.

conclusionTo reduce malaria's burden in Madagascar, strengthening healthcare systems, improving supply chains, and expanding prevention efforts in underserved areas are critical. Recommendations include targeting vulnerable groups, enhancing healthcare access, and fostering international collaboration for resource allocation and equitable intervention access. Strategies should emphasize scaling up IRS, ITNs distribution, and SBCC to effectively combat malaria.

Indexed as

Healthcare DisparitiesMalariaHumansMadagascarHealth inequitiesMadagascarMalariaRural communitiesVulnerable populations

Identifiers

PMID41535888
PMCPMC12888438

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.