Evidence map›Paper›PMID 41535875›Full record

ArticleAddiction science & clinical practice2026

Treatment of alcohol use disorder via magnetic resonance-guided focused ultrasound ablation surgery.

Fang Wang, Halimureti Paerhati, Zhengyu Lin, Shuangbao Liu, Bomin Sun, Dianyou Li

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Addiction science & clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fang Wang *Department of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Halimureti Paerhati *Department of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Zhengyu LinDepartment of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Shuangbao LiuShanghai International Medical Center, Shanghai, 201315, China.
Bomin SunDepartment of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Dianyou LiDepartment of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ldy11483@rjh.com.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol use disorder (AUD) is a problematic pattern of drinking that can cause significant impairment or distress. Magnetic resonance-guided focused ultrasound (MRgFUS) is a novel noninvasive technique permitting incision-less ablative treatment, which may be effective for AUD. CASE PRESENTATION: We present the case of a 54-year-old man diagnosed with AUD for 30 years. After bilateral nucleus accumbens (NAc) MRgFUS, his craving for alcohol decreased markedly from 6 to 0, and he remained abstinent throughout the follow-up (12 months). Moreover, psychiatric and neuropsychological assessments showed improvements in depression, anxiety, sleep, and quality of life. Besides, he did not have any serious adverse effects during the whole follow-up period.

conclusionsThis case report suggests the feasibility and potential of NAc ablation via MRgFUS in treating severe AUD. Subsequent multi-sample double-blind controlled trials need to be further studied. The effect of MRgFUS on the use disorders of other substances also requires further research.

Indexed as

AlcoholismMagnetic Resonance ImagingNucleus AccumbensHumansMaleMiddle AgedTreatment OutcomeAddictionAlcohol use disorderCase reportMagnetic resonance-guided focused ultrasoundNeuromodulationNucleus accumbens

Identifiers

PMID41535875
PMCPMC12853780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.