ArticleBMC nephrology2026
The incidence and risk factors of post-surgical AKI in a low resource setting: a prospective cohort study.
Article in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPost-surgical acute kidney injury (AKI) accounts for as much as a third of hospital acquired AKI. Post-surgical AKI is underreported in sub-Saharan Africa and it is associated with a longer hospital stay, a higher rate of readmission post-discharge, increased inpatient mortality, 1-year mortality, chronic kidney disease, and end-stage renal disease. The aim of this study is to determine the incidence of post-surgical AKI as well as to evaluate risk factors for post-surgical AKI.
methodThe study was a prospective cohort study carried out in Delta State University Teaching Hospital Oghara, Delta State. A total of seventy-nine participants billed to have either elective or emergency major abdominal surgery were recruited. Post-surgical AKI was diagnosed using the KDIGO serum creatinine criterion. Continuous variables were analysed using mean and median and were compared using the student T-test and Mann Whitney U test. Categorical variables were presented as frequencies and were compared using the chi-square test, Yates correction test and the fisher’s exact test as appropriate. The level of statistical significance was defined at p ≤ 0.05, at 95% confidence interval.
resultsSeventy-three participants were evaluated in this study with the modal age of 51–60 years and a median age of 44 years. The incidence of post –surgical AKI was 20.5%, more so patients with AKI were most likely to have a higher BMI (p < 0.0001), waist to hip ratio (p = 0.002), higher pulse rate and respiratory rate (p < 0.0001), higher temperature (p = 0.002), higher Revised cardiac risk index score (p = 0.02), higher fasting blood sugar (p = 0.001), longer duration of surgery, higher intraoperative blood loss(p = 0.04) and duration of anaesthesia (p = 0.001).
conclusionThe incidence of post-surgical AKI is high in low resource settings and measures can be taken to reduce the incidence and improve outcomes in the those with established risk factors.
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