Evidence map›Paper›PMID 41535789›Full record

ArticleBMC gastroenterology2026

Endoscopic balloon dilation for peptic gastroduodenal stenosis with gastric outflow obstruction: effectiveness, durability and early predictors of unsatisfactory outcomes.

Adam Zeyara, Léonie Scarfone, Martin Jeremiasen, Dan Falkenback, Bodil Andersson, Bobby Tingstedt, Jan Johansson

Abstract read
In one paragraph

Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam ZeyaraDepartment of Clinical Sciences, Lund University, Lund, Sweden. adam.zeyara@med.lu.se.
Léonie ScarfoneDepartment of Clinical Sciences, Lund University, Lund, Sweden.
Martin JeremiasenDepartment of Clinical Sciences, Lund University, Lund, Sweden.
Dan FalkenbackDepartment of Clinical Sciences, Lund University, Lund, Sweden.
Bodil AnderssonDepartment of Clinical Sciences, Lund University, Lund, Sweden.
Bobby TingstedtDepartment of Clinical Sciences, Lund University, Lund, Sweden.
Jan JohanssonDepartment of Clinical Sciences, Lund University, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeptic gastroduodenal stenosis is a rare but disabling condition causing gastric outlet obstruction. This study aimed to evaluate endoscopic balloon dilation in terms of treatment effectiveness, durability, and identify potential early predictors of unsatisfactory outcomes.

methodsWe conducted a retrospective cohort study of patients who underwent endoscopic balloon dilation for symptomatic peptic gastroduodenal stenosis at Skåne University Hospital, Lund, Sweden between January 1st, 2003, and December 31st, 2023.

resultsA total of 58 patients were included, with a median follow-up of 9.58 years [IQR 4.38–14.15]. Endoscopic balloon dilation was successful in 50 patients (86.2%), of whom 7 (14%) experienced symptomatic recurrence that was managed with repeat dilations. Eight patients were classified as non-responders and subsequently underwent surgical treatment. Kaplan–Meier curves identified three distinct response patterns among the responders: fast responders (0–1 months), intermediate responders (1-8 months), and slow responders (8-35 months), roughly corresponding to 1-2 dilations, 3-5 dilations, and 6 or more dilations, respectively. Undergoing more than five dilations had a significantly longer treatment duration and lower treatment effect compared with five or fewer dilations. Moreover, more than five dilations were associated with a significantly increased risk for recurrence (OR = 4.09; 95% CI 1.02–16.40, p = 0.047).

conclusionMost patients with peptic stenosis causing gastric outflow obstruction can be treated successfully with endoscopic balloon dilation alone. More than five dilations seem to be associated with a prolonged treatment period, lower treatment effect and increased risk for recurrence. These findings suggest that reconsideration of treatment strategy could be considered in patients who fail to improve after five dilations.

Indexed as

DilatationGastric Outlet ObstructionAgedConstriction, PathologicEndoscopy, GastrointestinalFemaleFollow-Up StudiesHumansKaplan-Meier EstimateMaleMiddle AgedRecurrenceRetrospective StudiesTreatment OutcomeEndoscopic balloon dilationGastricObstructionOutflowPepticStenosis

Identifiers

PMID41535789
PMCPMC12837236

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.