Evidence map›Paper›PMID 41535476›Full record

ArticleScientific reports2026

The expanding H5N1 avian influenza panzootic causes high mortality of skuas in Antarctica.

Matteo Iervolino, Anne Günther, Lineke Begeman, Begoña Aguado, Theo M Bestebroer, Beatriz Bellido-Martin, Adam Coerper, M Valentina Fornillo, Bruno Fusaro, Andrés E Ibañez and 12 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Matteo Iervolino *Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Anne Günther *Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.
Lineke BegemanDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Begoña AguadoCentro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Theo M BestebroerDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Beatriz Bellido-MartinDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Adam CoerperOcean Expeditions Support Vessel S/V Australis, Sydney, New South Wales, Australia.
M Valentina FornilloCentro de Estudios Parasitológicos y de Vectores (CEPAVE), CONICET - Universidad Nacional de La Plata, La Plata, Argentina.
Bruno FusaroDepartamento de Ecofisiología y Ecotoxicología, Instituto Antártico Argentino; San Martín, Buenos Aires, Argentina.
Andrés E IbañezSección Ornitología, Div. Zool. Vert. Museo de la Plata (FCNyM-UNLP-CONICET), La Plata, Argentina.
Lonneke LeijtenDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Simeon LisovskiAlfred Wegener Institute Helmholtz Centre for Polar and Marine Research, Potsdam, Germany.
Mariané B MañezCentro de Estudios Parasitológicos y de Vectores (CEPAVE), CONICET - Universidad Nacional de La Plata, La Plata, Argentina.
Alice ReadeOcean Expeditions Support Vessel S/V Australis, Sydney, New South Wales, Australia.
Peter van RunDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.
Florencia SotoInstituto de Biología de Organismos Marinos (IBIOMAR-CONICET), Puerto Madryn, Argentina.
Ben WallisOcean Expeditions Support Vessel S/V Australis, Sydney, New South Wales, Australia.
Meagan DewarFuture Regions Research Centre, Federation University Australia, Berwick, Victoria, Australia.
Antonio AlcamíCentro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Martin BeerInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.
Ralph E T VanstreelsSchool of Veterinary Medicine, Karen C. Drayer Wildlife Health Center, One Health Institute, University of California, Davis, Davis, CA, USA.
Thijs KuikenDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands. t.kuiken@erasmusmc.nl.

Funding

Consejo Superior de Investigaciones Científicas 202320E224European Union, Kappa-Flu 101084171
6 · The paper itself

Abstract

High pathogenicity avian influenza virus H5N1 subtype (H5N1 HPAIV), clade 2.3.4.4b, is expanding its host and geographical range, and invaded Antarctica in 2023. Although mortality in Antarctic wildlife from H5N1 HPAIV has been suspected, mainly based on virological analysis of swabs collected from dead animals, it has not been unequivocally diagnosed. Here we show that H5N1 HPAIV caused high mortality in a breeding colony of skuas at one of ten sites in Antarctica we visited in March 2024. By combined virological, bacteriological and pathological analyses, we found that H5N1 HPAIV caused multi-organ necrosis and rapid death in skuas, but not in other species examined. Taken together with recent data, skuas in Antarctica are at risk of continued mortality from H5N1 HPAIV infection, threatening their already small populations. Conversely, because of their wide distribution and ecological relevance, skuas may play a substantial role in the spread of the virus across Antarctica. Transdisciplinary surveillance is needed in coming years to monitor the impact of this poultry-origin disease on Antarctica’s unique wildlife.

Indexed as

CharadriiformesInfluenza A Virus, H5N1 SubtypeInfluenza in BirdsAnimalsAnimals, WildAntarctic Regions

Identifiers

PMID41535476
PMCPMC12868857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.