Evidence map›Paper›PMID 41535363›Full record

ArticleScientific reports2026

Metabolic interactions between bacterial co-isolates from catheter-associated urinary tract infections.

Dmytro Sokol, Olena Rzhepishevska, Iryna Marynova, Tor Monsen, Henrik Antti, Madeleine Ramstedt

Erratum issuedAbstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Dmytro SokolDepartment of Chemistry, Umeå Centre of Microbial Research, Umeå University, Umeå, Sweden.
Olena RzhepishevskaDepartment of Chemistry, Umeå Centre of Microbial Research, Umeå University, Umeå, Sweden.
Iryna MarynovaDepartment of Chemistry, Umeå Centre of Microbial Research, Umeå University, Umeå, Sweden.
Tor MonsenDepartment of Clinical Microbiology, Umeå University, Umeå, Sweden.
Henrik AnttiDepartment of Chemistry, Umeå Centre of Microbial Research, Umeå University, Umeå, Sweden.
Madeleine RamstedtDepartment of Chemistry, Umeå Centre of Microbial Research, Umeå University, Umeå, Sweden. madeleine.ramstedt@umu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catheter-associated urinary tract infections (CAUTI) are complex infections often involving multi-species bacteria. Escherichia coli is frequently an early coloniser. Subsequent colonisation by Pseudomonas aeruginosa and coexistence mechanisms between the two strains within urethral catheters is not yet fully understood. In this study, metabolic adaptations between co-isolated clinical E. coli and P. aeruginosa strains were investigated. It was found that P. aeruginosa outgrew E. coli in artificial urine medium (AUM), whereas E. coli dominated in culture broth such as Iso-sensitest. No evidence of direct antagonism was observed. Metabolite analyses revealed distinct metabolite patterns indicating cross-feeding and metabolic adaptations. In AUM, stress-response metabolites were elevated. Additionally, E. coli appeared to experience Fe-limitation in AUM, while the same was not observed for P. aeruginosa. The results highlight the influence of nutrient conditions on processes within mixed biofilms.

Indexed as

Catheter-Related InfectionsEscherichia coliPseudomonas aeruginosaUrinary Tract InfectionsBiofilmsHumans

Identifiers

PMID41535363
PMCPMC12808099

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.