Evidence map›Paper›PMID 41535263›Full record

ArticleCell death & disease2026

TRIP13 promotes the expansion and immunosuppression of CD4

Tianzhen He, Liwen Zhao, Chu-Ting Feng, Li-Ya Zhao, Shengnan Jing, Han Yang, Ke Wang, Siyu Ye, Yingchun Zhao, Ying Yu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tianzhen He *Institute of Pain Medicine and Special Environmental Medicine, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China. sailing198562@ntu.edu.cn.ORCID http://orcid.org/0000-0001-7873-853X
Liwen Zhao *Institute of Pain Medicine and Special Environmental Medicine, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China.
Chu-Ting FengInstitute of Pain Medicine and Special Environmental Medicine, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China.
Li-Ya ZhaoInstitute of Pain Medicine and Special Environmental Medicine, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China.
Shengnan JingInstitute of Pain Medicine and Special Environmental Medicine, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China.
Han YangDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shangdong, China.
Ke WangDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shangdong, China.ORCID http://orcid.org/0000-0002-5073-4200
Siyu YeInstitute of Pain Medicine and Special Environmental Medicine, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China.ORCID http://orcid.org/0000-0003-3040-1545
Yingchun ZhaoAffiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Ying YuAffiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Zhuting FuAnalysis and Testing Center, Nantong University, Nantong, Jiangsu, China.
Chon-Kit ChouState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade Taipa, Macau, SAR, China.
Xin ChenState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade Taipa, Macau, SAR, China.ORCID http://orcid.org/0000-0002-2628-4027
Yong-Jing GaoInstitute of Pain Medicine and Special Environmental Medicine, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu, China. gaoyongjing@ntu.edu.cn.ORCID http://orcid.org/0000-0002-7432-7458

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32030048National Natural Science Foundation of China (National Science Foundation of China) 82100557National Natural Science Foundation of China (National Science Foundation of China) 82271256
6 · The paper itself

Abstract

There is compelling evidence that TNF preferentially activates and expands CD4

Indexed as

ATPases Associated with Diverse Cellular ActivitiesForkhead Transcription FactorsHistone AcetyltransferasesT-Lymphocytes, RegulatoryAnimalsCell Cycle ProteinsCell ProliferationColitisDNA-Binding ProteinsHumansLysine Acetyltransferase 5MiceMice, Inbred C57BLNuclear ProteinsReceptors, Tumor Necrosis Factor, Type IITrans-ActivatorsATPases Associated with Diverse Cellular ActivitiesBanp protein, mouseCell Cycle ProteinsDNA-Binding ProteinsForkhead Transcription FactorsFoxp3 protein, mouseHistone AcetyltransferasesKat5 protein, mouseLysine Acetyltransferase 5Nuclear ProteinsReceptors, Tumor Necrosis Factor, Type IITrans-ActivatorsTumor Necrosis Factor-alpha

Identifiers

PMID41535263
PMCPMC12804696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.