Evidence map›Paper›PMID 41535051›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Mucous Membrane Pemphigoid during CPX-351 Therapy Successfully Treated with Corticosteroids.

Masahiro Akimoto, Takashi Matsuki, Michiki Saito, Kengo Katsuki, Takayoshi Tachibana, Masatsugu Tanaka, Hideaki Nakajima

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Masahiro AkimotoDepartment of Hematology, Kanagawa Cancer Center, Japan.
Takashi MatsukiDepartment of Head and Neck Surgery, Kanagawa Cancer Center, Japan.
Michiki SaitoDepartment of Hematology, Kanagawa Cancer Center, Japan.
Kengo KatsukiDepartment of Hematology, Kanagawa Cancer Center, Japan.
Takayoshi TachibanaDepartment of Hematology, Kanagawa Cancer Center, Japan.
Masatsugu TanakaDepartment of Hematology, Kanagawa Cancer Center, Japan.
Hideaki NakajimaDepartment of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 58-year-old man was diagnosed with acute myeloid leukemia with myelodysplasia-related changes. Induction therapy with CPX-351 achieved complete remission, and a second course of consolidation therapy was administered. Shortly after the second course, he developed aphthous ulcers on the tongue that progressively worsened. Although a tongue biopsy showed no specific findings, serum anti-bullous pemphigoid 180 antibodies were positive. Mucous membrane pemphigoid (MMP) was diagnosed, and corticosteroid therapy led to a rapid improvement. Given the temporal relationship between CPX-351 administration and the MMP onset, CPX-351 was considered to be the likely causative agent.

Indexed as

Adrenal Cortex HormonesPemphigoid, Benign Mucous MembraneHumansLeukemia, Myeloid, AcuteMaleMiddle AgedTreatment OutcomeAdrenal Cortex Hormonesacute myeloid leukemiaCPX-351mucous membrane pemphigoid

Identifiers

PMID41535051
PMCPMC13627609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.