Evidence map›Paper›PMID 41534877›Full record

ArticleACS nano2026

Ultrasmall Surface-Charge-Modified Tantalum Oxide Nanoparticles for the Assessment of Articular Cartilage Using Contrast-Enhanced Computed Tomography.

Jiri Jäntti, Juuso Tuppurainen, Anisha Joenathan, Henri P P Leskinen, Annunzia M Cagnoni, Heta Mertano, Milka Poimala, Ervin Nippolainen, Isaac O Afara, Juuso T J Honkanen and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jiri JänttiDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.ORCID 0000-0001-8442-8458
Juuso TuppurainenDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.
Anisha JoenathanDivision of Materials Science, Boston University, Boston, Massachusetts 02215, United States.
Henri P P LeskinenDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.
Annunzia M CagnoniDepartment of Biomedical Engineering, The University of Melbourne, Melbourne 3010, Australia.
Heta MertanoDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.ORCID 0000-0003-1954-9573
Milka PoimalaDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.ORCID 0009-0000-5779-1307
Ervin NippolainenDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.
Isaac O AfaraDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.
Juuso T J HonkanenCenter of Oncology, Kuopio University Hospital, Wellbeing Services County of North Savo, Kuopio 70210, Finland.
Hanna MatikkaICMT and Development Services, Kuopio University Hospital, Wellbeing Services County of North Savo, Kuopio 70210, Finland.
Juha TöyräsDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.
Brian D SnyderDepartment of Orthopedic Surgery, Boston Children's Hospital, Boston, Massachussets 02115, United States.
Kathryn S StokDepartment of Biomedical Engineering, The University of Melbourne, Melbourne 3010, Australia.
Brad B NelsonOrthopaedic Research Center, C. Wayne McIlwraith Translational Medicine Institute, Colorado State University, Fort Collins, Colorado 80523, United States.
Mark W GrinstaffDivision of Materials Science, Boston University, Boston, Massachusetts 02215, United States.ORCID 0000-0002-5453-3668
Janne T A MäkeläDepartment of Technical Physics, University of Eastern Finland, Kuopio 70211, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The size and surface properties of nanoparticles (NPs) define their interactions with biological tissues and impact their effectiveness for targeted imaging and therapeutic applications. Here, we investigate ultrasmall tantalum oxide nanoparticles (Ta

Indexed as

Cartilage, ArticularContrast MediaNanoparticlesOxidesTantalumTomography, X-Ray ComputedAnimalsHorsesHumansOsteoarthritisParticle SizeRabbitsSurface PropertiesContrast MediaOxidesTantalumtantalum oxidecartilage imagingcontrast agentlesionsmicrocomputed tomographynanoparticlesosteoarthritis

Identifiers

PMID41534877
PMCPMC12854743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.