Evidence map›Paper›PMID 41533866›Full record

SynthesisTranslational vision science & technology2025

Ocular Surface Disorders in ICU Patients: Evidence-Based Nursing Prevention Strategies.

Weiwei Ni, Xinwei Jiao

Abstract readSystematic Review
In one paragraph

Synthesis in Translational vision science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Weiwei NiNursing Department, Affiliated Hospital of Shandong Second Medical University, Weifang Key Laboratory for Clinical Nursing Research, Weifang, People's Republic of China.
Xinwei JiaoDepartment of Ophthalmology, Affiliated Hospital of Shandong Second Medical University, School of Clinical Medicine, Shandong Second Medical University, Weifang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This review evaluates the epidemiology, risk factors, and effectiveness of nursing interventions for preventing ocular surface disorders in intensive care unit (ICU) patients from 2020 to 2025. Methods: A systematic review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, with study quality and bias assessed using standardized tools. Comprehensive searches of 6 databases from January 2020 to May 2025 identified 40 eligible studies on ocular surface disorders in ICU patients, including randomized trials, cohort studies, and meta-analyses. Due to heterogeneity, a narrative synthesis was used. Risk of bias was assessed with ROBINS-I and Cochrane tools, with subgroup analyses based on ventilation status and ICU type. Results: The incidence of ocular surface disorders in intensive care unit patients ranged from 20% to 60%, with dry eye disease (DED) occurring in 40%, exposure keratopathy in 23%, and conjunctivitis in 25% of cases. Major risk factors included mechanical ventilation, incomplete eyelid closure, prolonged sedation, and low environmental humidity. Multimodal nursing interventions that combined eyelid closure, ocular lubrication, moisture chamber application, and staff education effectively reduced the incidence of corneal injury from 69.7% to 13.8% in high-risk patients. Passive blinking exercises demonstrated significant effectiveness and feasibility in low-resource settings. Conclusions: Ocular surface disorders are common in ICU patients but can be effectively prevented through standardized care, eye protection, lubrication, and staff training. Incorporating eye care into daily routines improves safety and visual outcomes, whereas simple measures like passive blinking remain practical and valuable.

Indexed as

Dry Eye SyndromesEvidence-Based NursingIntensive Care UnitsCorneal DiseasesHumansIncidenceRisk Factors

Identifiers

PMID41533866
PMCPMC12743487

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.