Evidence map›Paper›PMID 41533806›Full record

ArticleNutrition and health2026

Weight loss at a cost: A case of sibutramine-induced psychotic disorder.

Keerthi Raj, Tsz Yuen Au, Sanoj Jacob, Jatinder Kour

Abstract readCase Reports
In one paragraph

Article in Nutrition and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Keerthi RajCommunity Mental Health Service for Working Age, St Mary's Hospital, Leeds, UK.
Tsz Yuen AuFaculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-6709-4174
Sanoj JacobMental Health Services for Older Adults (MHSOP), Horton Park Medical Centre, Bradford, UK.
Jatinder KourRoseberry Park Hospital, Middlesbrough, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundSibutramine was once a commonly prescribed medication for weight management. However, it was ultimately removed from the market due to its link to serious cardiovascular risks such as stroke and myocardial infarction. While its primary function is to suppress appetite, sibutramine has also been known to trigger a range of psychiatric symptoms, including anxiety, depression, and psychosis.ObjectiveTo present a case highlighting the potential mental health implications associated with the use of sibutramine.MethodsThis article presents a case report; clinical details were documented by the psychiatrist in charge and reviewed by the team. The Naranjo adverse drug reaction Probability Scale was used in this case to evaluate whether the psychotic events were associated with sibutramine use.Resultsa young female developed severe psychiatric symptoms requiring hospitalization after using sibutramine for weight loss. Treatment included suspending sibutramine and administering Aripiprazole 15 mg.ConclusionThis case serves as a poignant reminder of the potential dangers associated with using unregulated medications for weight loss purposes and underscores the importance of seeking professional medical guidance when embarking on any kind of treatment regimen.

Indexed as

Appetite DepressantsCyclobutanesPsychoses, Substance-InducedPsychotic DisordersWeight LossFemaleHumansAppetite DepressantsCyclobutanessibutraminePsychotic disordersibutramineweight loss

Identifiers

PMID41533806
PMCPMC13096613

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.