Evidence map›Paper›PMID 41533796›Full record

ArticleScience advances2026

Revitalizing poly(urea)s via disulfide reconfiguration.

Zezhou Zong, Da-Hui Qu, He Tian, Qi Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zezhou ZongKey Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.ORCID 0009-0008-7873-0114
Da-Hui QuKey Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.ORCID 0000-0002-2039-3564
He TianKey Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.ORCID 0000-0003-3547-7485
Qi ZhangKey Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.ORCID 0000-0001-8616-5452

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Weak bonds are well-known to construct soft materials. Elaborating molecule-level self-assembly via supramolecular engineering could generate performance materials that exhibit high strength at mild temperatures. However, the entropy penalty of assembled materials, meanwhile, compromises robustness at elevated temperatures. Herein, we report that simply replacing two carbons with disulfide bonds in poly(urea)s enables unprecedented structural reconfigurability without trading off material robustness. Introducing disulfide bonds maintains the ordered urea-based H-bond assembly in bulk polymers while simultaneously suppressing secondary crystallization of these H-bonded arrays and offering secondary H-bonding sites by forming S─S·H─N interactions. This two-atom structural change revitalizes semicrystalline homopoly(urea) materials by allowing chain mobility and reconfiguration below melting temperatures to enable thermoplastic-like (re)processability and thermoset-like robustness, including more than 2-gigapascal storage modulus, a broad creep-resistant temperature range (up to 150°C), ceramic-like hardness, and resistance to common solvents. Furthermore, these materials exhibit acid-catalyzed depolymerization potential, enabling closed-loop recyclability.

Identifiers

PMID41533796
PMCPMC12802836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.