Evidence map›Paper›PMID 41533794›Full record

ArticleScience advances2026

An ancient genome duplication event drives the development and evolution of spinnerets in spiders.

Fengyuan Li, Han Yang, Yiming Zhang, Shuhui Wang, Qi Gu, Meiming Wu, Pengyu Jin, Xin Huang, Yu Zhong, Xianting Huang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fengyuan LiState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0001-9437-5732
Han YangState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0009-0001-9675-512X
Yiming ZhangState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0001-8547-6654
Shuhui WangState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Qi GuState Key Laboratory of Membrane Biology and the State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0001-9387-9525
Meiming WuState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Pengyu JinCollege of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.ORCID 0000-0003-1310-2711
Xin HuangState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0009-0009-7879-9717
Yu ZhongState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0009-0007-4961-757X
Xianting HuangState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Yejie LinCollege of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.ORCID 0000-0002-6789-2731
Xinyue GuoCollege of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Yunyun LiCollege of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Wei ZhangState Key Laboratory of Gene Function and Modulation Research, School of Life Sciences, Peking University, Beijing 100871, China.ORCID 0000-0002-6644-7046
Shuqiang LiCollege of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.ORCID 0000-0002-3290-5416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key appendage innovations have driven the origin and expansion of arthropods, such as spinnerets enabling spiders to occupy three-dimensional space and diversify into more than 53,000 species. Here, we investigate the genetic basis of spinneret emergence in spiders by examining the complex history and functional importance of arachnid genome evolution. Using chromosome-scale genomes from newly sequenced spiders and the whip scorpion, we integrate evidence from macrosynteny and phylogenetic analyses to provide further strong support for a whole-genome duplication (WGD) event that occurred during early Arachnopulmonata evolution. Following this event, the

Indexed as

Biological EvolutionEvolution, MolecularGene DuplicationGenomeSpidersAnimalsGenomicsPhylogeny

Identifiers

PMID41533794
PMCPMC12802834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.