ArticleChemistry, an Asian journal2026
Pyridine and N-Pyridinium Functionalized Macrocyclic Squaramide Anion Receptors with High Affinity for Aqueous Sulfate.
Article in Chemistry, an Asian journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Macrocyclic squaramide-containing receptors have previously been shown to bind sulfate with high selectivity and affinity in aqueous-organic mixtures. To increase binding affinity of this class of hydrogen-bonding receptors in pure water, macrocycles in which pyridinium groups have been inserted to provide additional charge-assisted hydrogen-bonding interactions were synthesized and their anion binding evaluated. The inclusion of charge-assisted interactions provides enhanced binding affinity for sulfate in water but concomitantly reduces ability of the receptors to discriminate sulfate from the closely related selenate and leads to unexpected changes in binding stoichiometry.
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