Evidence map›Paper›PMID 41533648›Full record

ArticleChemistry, an Asian journal2026

Enhanced Marine Biodegradability of Poly(Lactic Acid)-Based Polyurethanes via Alkylene Diglycolate Incorporation.

Yuushou Nakayama, Chigen Kinoshita, Ryo Tanaka, Takeshi Shiono, Shodai Hino, Norioki Kawasaki, Naoko Yamano, Atsuyoshi Nakayama

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry, an Asian journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuushou NakayamaDepartment of Applied Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.ORCID https://orcid.org/0000-0002-8049-0788
Chigen KinoshitaDepartment of Applied Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Ryo TanakaDepartment of Applied Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Takeshi ShionoDepartment of Applied Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Shodai HinoMolecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan.
Norioki KawasakiMolecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan.
Naoko YamanoMolecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan.
Atsuyoshi NakayamaMolecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(L-lactic acid) (PLLA) is a widely used biodegradable polymer with potential environmental applications. However, its biodegradability under marine conditions is limited, especially for high molecular weight variants. This study aims to develop PLLA-based materials with enhanced biodegradability in seawater by incorporating alkylene diglycolate structures into the polymer backbone. Novel PLLA-based polyurethanes (PLLAUs) were synthesized via ring-opening polymerization of L-lactide using alkylene diglycolates as initiators, followed by chain extension with hexamethylene diisocyanate. The biodegradability of the PLLAUs in seawater was evaluated using biochemical oxygen demand (BOD) measurements. The incorporation of alkylene diglycolate structures facilitated degradation by accelerating the slow extracellular hydrolysis stage, which is responsible for the poor biodegradability of high molecular weight PLLA. The results indicated that PLLAUs containing alkylene diglycolate segments exhibited greater biodegradability than conventional PLLA of similar molecular weight in seawater. The PLLAUs also exhibited greater tensile strength and elongation at break compared to conventional PLLA.

Indexed as

alkylene diglycolatemarine biodegradabilitypoly(L‐lactic acid)polyurethane

Identifiers

PMID41533648
PMCPMC12803487

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.