Evidence map›Paper›PMID 41533644›Full record

ArticlePloS one2026

Associations between sleep duration and depression, mental health, physical health, and general health in U.S. adults: A population-based study.

Mojisola Fasokun, Oluwasegun Akinyemi, Fadeke Ogunyankin, Phiwinhlanhla Ndebele-Ngwenya, Kaelyn Gordon, Seun Ikugbayigbe, Uzoamaka Nwosu, Mariam Michael, Kakra Hughes, Temitope Ogundare

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Sleep Health Disparities: Are Black Women Disadvantaged?Journal of racial and ethnic health disparities · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mojisola FasokunDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Oluwasegun AkinyemiThe Clive O Callender Outcomes Research Center, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Fadeke OgunyankinDepartment of Research Data Science and Analytics, Cook Children's Health Care System: Cook Children's Medical Center, Fort Worth, Texas, United States of America.ORCID 0009-0004-8461-9659
Phiwinhlanhla Ndebele-NgwenyaThe Clive O Callender Outcomes Research Center, Howard University College of Medicine, Washington, District of Columbia, United States of America.ORCID 0009-0007-1600-0266
Kaelyn GordonThe Clive O Callender Outcomes Research Center, Howard University College of Medicine, Washington, District of Columbia, United States of America.ORCID 0009-0006-5627-9655
Seun IkugbayigbeDepartment of Biological Sciences, Eastern Illinois University, Charleston, Illinois, United States of America.ORCID 0009-0009-1273-0688
Uzoamaka NwosuDepartment of Psychiatry and Behavioral Sciences, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Mariam MichaelDepartment of Internal Medicine, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Kakra HughesDepartment of Surgery, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Temitope OgundareDepartment of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, United States of America.

Funding

Sleep Disorders in Adults with Sickle Cell Disease: Frequency, Associations with Cardiovascular and Pain Indicators, and Responses to TreatmentU54MD007597 · NIMHD · HOWARD UNIVERSITY · PI BYRON D. FORD · 2019 to 2026
$37.7M
NIMHD NIH HHS U54 MD007597
6 · The paper itself

Abstract

introductionAdequate sleep is vital for maintaining mental and physical health. In the United States, a substantial proportion of adults report sleep durations that fall outside the recommended range. Prior research has associated insufficient or excessive sleep with adverse health outcomes; however, few studies have systematically quantified these associations across multiple health indicators using nationally representative data.

objectiveThis study aims to evaluate the impact of short sleep duration on four key health outcomes: depression diagnosis, number of self-reported poor mental health days, number of physically unhealthy days, and self-rated general health status, using nationally representative U.S. data. METHODOLOGY:

methodsWe analyzed nationally representative data from the Behavioral Risk Factor Surveillance System (BRFSS) collected between 2016 and 2023. Sleep duration was self-reported and categorized into three groups: short sleep (≤5 hours), recommended sleep (6-8 hours), and long sleep (≥9 hours), with short sleep serving as the reference category. The primary health outcomes included: (1) self-reported diagnosis of depression, (2) number of poor mental health days, (3) number of poor physical health days, and (4) self-rated general health, measured on a 5-point Likert scale from excellent to poor. To estimate the effect of sleep duration on these outcomes, we applied Inverse Probability Weighting (IPW) to derive the Average Treatment Effect (ATE), adjusting for key demographic and socioeconomic covariates. All analyses incorporated BRFSS complex survey weights to ensure national representativeness.

resultsThe study included 318,000 adults (63.3% female; 74.5% White) with a mean age of 51.3 ± 18.4 years. Among individuals with recommended sleep duration (6-8 hours), the baseline prevalence of depression was 39.5% (95% CI: 39.4%-39.7%). Compared to this group, short sleep duration (≤5 hours) was associated with a 14.1 percentage point increase in depression incidence (95% CI: 13.8%-14.4%), while long sleep duration (≥9 hours) was linked to a 12.9 percentage point increase (95% CI: 12.5%-13.3%). Those with short sleep reported an average of 5.3 poor mental health days (95% CI: 5.3-5.4), 4.4 poor physical health days (95% CI: 4.3-4.4), and a higher prevalence of poor general health, 10.0% (0.1, 95% CI: 9.7%-10.2%), compared to individuals with recommended sleep. Similarly, individuals with long sleep duration (≥9 hours) also reported more poor mental (4.6 days, 95% CI: 4.5-4.7) and physical health days (3.2 days, 95% CI: 3.1-3.3), along with a higher prevalence of poor general health, 20.3% (20.3%%, 95% CI 19.4%-21.3%) compared to those with recommended sleep.

conclusionBoth short (≤5 hours) and long (≥9 hours) sleep durations are significantly associated with increased risk of depression, more days of poor mental and physical health, and worse self-rated general health compared to recommended sleep (6-8 hours). Promoting optimal sleep duration through targeted public health interventions, education, and screening may improve population well-being and reduce sleep-related health disparities.

Indexed as

DepressionHealth StatusMental HealthSleepSleep DurationAdultAgedBehavioral Risk Factor Surveillance SystemFemaleHumansMaleMiddle AgedSelf ReportUnited StatesYoung Adult

Identifiers

PMID41533644
PMCPMC12803467

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.