ArticleChemistry, an Asian journal2026
Palladium-Catalyzed Decarboxylative C─H Alkenylation of Proaromatic Acids With Allyl Alcohols and N-Allyl Sulfonamides.
Article in Chemistry, an Asian journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We develop an efficient palladium-catalyzed decarboxylative C─H alkenylation of cyclohexa-2,5-dienyl carboxylic acids with allylic alcohols and N-allyl sulfonamides, enabling regioselective access to diverse vinylarenes. The transformation proceeds under mild, operationally simple conditions and tolerates a broad range of alkyl, aryl, and heteroaryl substituents. Mechanistic studies reveal that the reaction is going via carboxylate-directed C─H activation and olefin insertion step. The method is scalable and offers a practical route to vinylarene scaffold-containing biologically relevant moieties.
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