Evidence map›Paper›PMID 41533270›Full record

ArticleJournal of autism and developmental disorders2026

Telehealth-Based Parent-Mediated Pivotal Response Treatment for Preschool Children With Autism Spectrum Disorder: A Pilot Randomized Controlled Study.

Pou-Leng Cheong, Ming-Chen Lin, Chien-Heng Lin, Yen-Chin Wang, Yen-Ting Lai, Lin-Ju Kang, Hsiao-I Kuo, Yen-Tzu Wu, Tzu-Chun Hsu

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Article in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pou-Leng Cheong *Department of Pediatrics, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
Ming-Chen Lin *School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chien-Heng LinDepartment of Psychiatry, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu County, Hsinchu, Taiwan.
Yen-Chin WangDepartment of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.
Yen-Ting LaiDepartment of Pediatrics, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
Lin-Ju KangGraduate Institute of Early Intervention, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Hsiao-I KuoSchool and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yen-Tzu WuSchool and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan. yenwu@ntu.edu.tw.ORCID http://orcid.org/0000-0001-5035-4577
Tzu-Chun HsuSchool and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.

Funding

National Taiwan University Hospital Hsin-Chu Branch 112-HCH110 and 113-HCH003
6 · The paper itself

Abstract

purposeThis pilot randomized controlled trial examined the feasibility, acceptability, and preliminary effectiveness of a telehealth-based Pivotal Response Treatment (TPRT) program for preschool children with autism spectrum disorder (ASD) in Taiwan, where access to evidence-based, parent-mediated interventions remains limited in underserved communities.

methodsFifty children aged 24-72 months were randomly assigned to either the intervention group, which received a 12-week therapist-guided TPRT program, or the control group receiving general parent support. Parents in the TPRT group attended weekly online coaching sessions and practiced the strategies daily at home. After the 12-week intervention, all participants entered a 4-week follow-up phase, during which TPRT parents independently practiced and applied the learned strategies in daily routines without therapist supervision, allowing evaluation of their autonomous use and short-term maintenance of treatment effects. Post-intervention assessments at the end of the follow-up evaluated child developmental outcomes and parental stress.

resultsCompared with controls, the TPRT group showed significantly greater improvements in language and motor development, with medium-to-large effect sizes in adaptive functioning, particularly in daily living and motor domains. Parenting stress significantly decreased, with most parents reporting reduced distress and improved perceptions of child behavior. Program adherence was high (88% daily strategy use, 85% homework completion), and parental satisfaction averaged 93%.

conclusionsThe TPRT program was feasible, well accepted, and associated with meaningful developmental and parental benefits. Findings support the promise of telehealth-delivered, parent-mediated PRT as a scalable model to improve service accessibility for young children with ASD in underserved settings.

Indexed as

Autism spectrum disorderEarly interventionParent-mediated interventionPivotal response treatmentPreschoolTelehealth

Identifiers

PMID41533270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.