Evidence map›Paper›PMID 41533258›Full record

ArticleJapanese journal of ophthalmology2026

Comparison of the effectiveness between propensity score-matched trabecular micro-bypass stent versus ab interno trabeculotomy.

Suguru Nakagawa, Satoru Kanda, Kiyohito Totsuka, Yi-Ning Chen, Kimiko Okinaga, Mitsuko Takamoto, Kiyoshi Ishii

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suguru NakagawaDepartment of Ophthalmology, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama-shi, Saitama, Japan. snakagawa-tky@umin.ac.jp.ORCID http://orcid.org/0000-0001-9938-4881
Satoru KandaDepartment of Ophthalmology, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama-shi, Saitama, Japan.
Kiyohito TotsukaDepartment of Ophthalmology, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama-shi, Saitama, Japan.
Yi-Ning ChenDepartment of Ophthalmology, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama-shi, Saitama, Japan.
Kimiko OkinagaDepartment of Ophthalmology, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama-shi, Saitama, Japan.
Mitsuko TakamotoDepartment of Ophthalmology, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama-shi, Saitama, Japan.
Kiyoshi IshiiDepartment of Ophthalmology, Saitama Red Cross Hospital, 1-5 Shintoshin, Chuo-ku, Saitama-shi, Saitama, Japan.

Funding

Japan Society for the Promotion of Science London 25K12854
6 · The paper itself

Abstract

purposeTo assess the efficacy of trabecular micro-bypass stents (IS) versus ab interno trabeculotomy (LOT) performed alongside cataract surgery; and to ensure patient comparability across both surgical groups concerning age, intraocular pressure (IOP), medication score, and disease type. STUDY

designRetrospective cohort

methodsOverall, 194 eyes were assessed from 107 Japanese patients with open-angle glaucoma or exfoliation glaucoma who received IS plus cataract surgery at Saitama Red Cross Hospital between July 2017 and January 2022. Another 88 eyes were assessed from 58 patients who underwent combined LOT and cataract surgery at the same hospital between January 2018 and December 2019. Both cohorts were followed-up for ≥6 months. Propensity scoring facilitated between-group patient background matching. Overall, 62 eyes per group matched for preoperative characteristics were analyzed.

resultsSix-month postoperative IOP was 14.50 ± 2.26 and 14.08 ± 2.50 mmHg for IS and LOT, respectively, with medication scores of 1.50 ± 1.17 (IS) and 1.71 ± 1.60 (LOT), indicating no significant differences. The IOP reduction rate was 19.03 ± 13.34% (IS) and 18.94 ± 23.26% (LOT), showing no significant difference. Both groups exhibited similar medication score reductions (-1.11 ± 1.04 [IS], and -0.92 ± 1.47 [LOT]). Preoperative IOP significantly correlated with IOP reduction rate in both procedures. LOT patients experienced more hyphema postoperatively, versus IS patients.

conclusionIn eyes with relatively well-controlled preoperative IOP-where either IS or LOT could be reasonably selected-either procedure offers similar surgical outcomes, with comparable postoperative performance and complication rates, except for postoperative hyphema.

Indexed as

Exfoliation SyndromeGlaucoma Drainage ImplantsGlaucoma, Open-AngleIntraocular PressurePropensity ScoreStentsTrabecular MeshworkTrabeculectomyVisual AcuityAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedAb interno trabeculotomyCataract surgeryMinimally invasive glaucoma surgeryOpen-angle glaucomaTrabecular micro-bypass stent

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.