Evidence map›Paper›PMID 41533204›Full record

SynthesisMusculoskeletal surgery2026

Meta-analytic evaluation of complications and longevity of bone-anchored prostheses in lower extremity amputees: does design matter?

Hugh Milchem, Yasmine J Khair, Maamoun Adra, Shayndhan S Sivanathan, Shreehari Suresh, Dilip K Vankayalapati, Aslam Mohamed Haroon, Christian A Than, Nadim Tarazi, Hayato Nakanishi and 1 more

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Musculoskeletal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Technological advances in amputation medicine].Chirurgie (Heidelberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hugh MilchemMedical School, University of Nicosia, Nicosia, 2408, Cyprus.
Yasmine J KhairMedical School, University of Nicosia, Nicosia, 2408, Cyprus.
Maamoun AdraCambridge University Hospitals NHS Foundation Trust, Addenbrookes Hospital, Cambridge, CB2 0QQ, UK.
Shayndhan S SivanathanOxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
Shreehari SureshOxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
Dilip K VankayalapatiOxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
Aslam Mohamed HaroonHull University Teaching Hospital NHS Trust, Hull Royal Infirmary, Anlaby Road, Hull, East Yorkshire, HU3 2JZ, UK.
Christian A ThanSchool of Biomedical Sciences, The University of Queensland, St Lucia, 4072, Brisbane, Australia. c.than@uq.edu.au.
Nadim TaraziCambridge University Hospitals NHS Foundation Trust, Addenbrookes Hospital, Cambridge, CB2 0QQ, UK.
Hayato NakanishiDepartment of Surgery, Mayo Clinic, Rochester, USA.
Peter J SmithamOrthopaedic and Trauma Department, Royal Adelaide Hospital, Adelaide, 5000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone-anchored prostheses (BAPs) are an alternative option for lower-limb amputees with problematic suspended socket prostheses (SSPs). We sought to meta-analytically quantify complication burden and revision-free survival for BAPs, whilst investigating possible differences in complication rates between common screw-fit (OPRA) and press-fit (ILP/OPL) designs. A multi-database search of PubMed, EMBASE, CiNAHL, Cochrane Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Scopus and Web of Science from inception to September 2025 was conducted. Proportions were pooled using a random-effects model. This review was registered in PROPSPERO (ID: CRD42024507070). A total of 22 studies reporting 979 patients were included. An overall complication rate of 65% (95% CI: 0.53-0.75, I

Indexed as

AmputeesArtificial LimbsBone-Anchored ProsthesisLower ExtremityPostoperative ComplicationsProsthesis DesignProsthesis FailureHumansAmputationBone-anchored prosthesisImplantOsseointegrationProsthesis

Identifiers

PMID41533204
PMCPMC13473266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.