Evidence map›Paper›PMID 41533165›Full record

ArticleMikrochimica acta2026

Integrating monolithic sorbent micro-solid-phase extraction with anodized screen-printed graphene electrode for serotonin neurotransmitter detection in the presence of ascorbic acid and uric acid.

Jeerakit Thangphatthanarungruang, Wichayaporn Kamsong, Kesara Ar-Sanork, Pattanun Ngaosri, Chanchai Charonpongsuntorn, Papan Thaipisuttikul, Warawut Tiyapongpattana, Patcharin Chaisuwan, Chanpen Karuwan

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeerakit ThangphatthanarungruangNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani, 12120, Thailand.
Wichayaporn KamsongNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani, 12120, Thailand.
Kesara Ar-SanorkNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani, 12120, Thailand.
Pattanun NgaosriNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani, 12120, Thailand.
Chanchai CharonpongsuntornDepartment of Internal Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, 26120, Thailand.
Papan ThaipisuttikulDepartment of Psychiatry, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Warawut TiyapongpattanaDepartment of Chemistry, Faculty of Science and Technology, Thammasat University, Khlong Luang, Pathum Thani, 12120, Thailand.
Patcharin ChaisuwanSchool of Chemistry, Institute of Science, Suranaree University of Technology, 111 University Avenue, Muang District, Nakhon Ratchasima, 30000, Thailand.
Chanpen KaruwanNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani, 12120, Thailand. chanpen.kar@nanotec.or.th.

Funding

National Research Council of Thailand (NRCT) N84A670509
6 · The paper itself

Abstract

A novel analytical method is proposed that integrates monolithic sorbent micro-solid-phase extraction (µ-SPE) with an anodized screen-printed graphene electrode for the determination of serotonin (SER). Monolithic sorbent µ-SPE offers a straightforward and efficient pretreatment method for removing of interfering substances, thereby enhancing the selectivity of SER analysis before being coupled with an electrochemical sensor. Under optimal conditions, the integration of monolithic sorbent µ-SPE with the electrochemical sensor provided a broad linear range of 50-1500 nM for SER detection, with detection and quantification limits of 4.78 and 15.94 nM, respectively. The developed sensor exhibited excellent reproducibility (RSD < 10%) and good stability over a period of 6 months. Furthermore, the proposed method can detect SER even in the presence of ascorbic acid and uric acid at their normal levels in human biological fluids. This method was successfully applied to determine SER levels in real urine samples with an acceptable recovery range of 93.76%-124.14%. The analytical results derived from the developed methodology are strongly correlated with those obtained using the standard high-performance liquid chromatography method.

Indexed as

ElectrodesGraphiteSerotoninSolid Phase MicroextractionAscorbic AcidHumansNeurotransmitter AgentsUric AcidAscorbic AcidGraphiteNeurotransmitter AgentsSerotoninUric AcidElectrochemical sensorMonolithic sorbentNeurotransmittersScreen-printed electrodeSerotoninSolid-phase extractionSquare wave voltammetry

Identifiers

PMID41533165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.