Evidence map›Paper›PMID 41532968›Full record

ArticleJournal of magnetic resonance imaging : JMRI2026

Non-Subtractive Arterial Spin Labeling-Based (NSASL) Renal Magnetic Resonance Angiography (MRA): Development and Clinical Feasibility Evaluation.

Yulin Wang, Ye Yuan, Kun Yan, Jichang Zhang, Jie Zeng, Shengyang Niu, Shiying Ke, Chendie Yao, Bin Chen, Qi Dai and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yulin WangDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.ORCID https://orcid.org/0000-0003-4824-1463
Ye YuanDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.ORCID https://orcid.org/0009-0007-9591-2262
Kun YanDepartment of Radiology, Ningbo Number 2 Hospital, Ningbo, Zhejiang, China.
Jichang ZhangDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.
Jie ZengDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.
Shengyang NiuDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.
Shiying KeDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.
Chendie YaoDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.
Bin ChenDepartment of Radiology, Ningbo Number 2 Hospital, Ningbo, Zhejiang, China.
Qi DaiDepartment of Radiology, Ningbo Number 2 Hospital, Ningbo, Zhejiang, China.
Liping GuoDepartment of Radiology, Ningbo Number 2 Hospital, Ningbo, Zhejiang, China.
Jianjun ZhengDepartment of Radiology, Ningbo Number 2 Hospital, Ningbo, Zhejiang, China.
Thomas MeersmannDepartment for Strategic Development of Health Science and Technology, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.
Chengbo WangDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, Zhejiang, China.ORCID https://orcid.org/0000-0001-9779-4713

Funding

National Key Research and Development Program of China 2022YFC240890Ningbo "S&T Innovation 2035" Major program 2023Z182Ningbo "S&T Innovation 2035" Major program 2025Z20
6 · The paper itself

Abstract

backgroundNon-contrast renal MR angiography (MRA) is valuable for patients who cannot receive contrast agents or when avoiding radiation is desired. However, the conventional inflow inversion recovery (IFIR) method is limited by incomplete background suppression, venous contamination, and motion sensitivity. PURPOSE: To develop and evaluate a non-subtractive arterial spin labeling-based (NSASL) sequence for renal MRA and compare it with IFIR in healthy volunteers, with exploratory feasibility assessment relative to contrast-enhanced (CE)-MRA or computed tomography angiography (CTA) in patients. STUDY TYPE: Prospective. SUBJECTS: Thirty healthy volunteers (10 male, 35.6 FIELD STRENGTH/SEQUENCE: 1.5 T; 3D stack-of-stars balanced steady-state free precession (bSSFP) NSASL MRA, 3D Cartesian bSSFP IFIR MRA, and CE-MRA. ASSESSMENT: Three radiologists independently rated image quality (main and branch renal arteries visualization, motion artifacts, vessel-to-background contrast, diagnostic confidence) on a 5-point scale. SNR efficiency (or SNR and time) and contrast ratio (CR) were also measured. STATISTICAL TESTS: Intraclass coefficient (ICC), Shapiro-Wilk's test, paired Student's t-test, and Wilcoxon signed-rank test with Bonferroni correction, with p < 0.05 considered statistically significant.

resultsICC was good to excellent (ICC = 0.61-0.89) for average subjective scores. Compared with IFIR, NSASL showed significantly better vessel-to-background contrast (approximately fivefold increase in CR, Cohen's |d| = 2.54; +1 subjective score, |r| = 0.88), improved renal arteries visualization (+0.7 points, |r| = 0.67, corrected p DATA

conclusionNSASL significantly outperformed IFIR, with improved background suppression, vessel conspicuity, motion tolerance, and scan time in healthy volunteers. EVIDENCE LEVEL: 2. TECHNICAL EFFICACY: Stage 2.

Indexed as

KidneyMagnetic Resonance AngiographyRenal ArteryAdultAgedArtifactsComputed Tomography AngiographyContrast MediaFeasibility StudiesFemaleHealthy VolunteersHumansImage Processing, Computer-AssistedImaging, Three-DimensionalKidney DiseasesMaleContrast MediaSpin Labelsarterial spin labeling (ASL)balanced steady‐state free precession (bSSFP)non‐contrast magnetic resonance angiography (MRA)renal artery

Identifiers

PMID41532968
PMCPMC13066539

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.