Evidence map›Paper›PMID 41532924›Full record

ArticleJACC. Case reports2026

The Degenerated Sutureless Valve in Full Root Prosthesis: A Tale of 2 Approaches.

Michele D'Alonzo, Antonio Davide Conserva, Emmanuel Villa, Antonio Messina, Marco Cirillo, Margherita Dalla Tomba, Gianluca Cullurà, Kiara Corigliano, Diego Maffeo, Giovanni Troise

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michele D'AlonzoCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy; Valve Center, Poliambulanza Foundation Hospital, Brescia, Italy. Electronic address: Michele.dalonzo@poliambulanza.it.
Antonio Davide ConservaCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy; Cardiac Surgery Specialization School, Catholic University of the Sacred Heart, Roma, Italy.
Emmanuel VillaCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy; Valve Center, Poliambulanza Foundation Hospital, Brescia, Italy.
Antonio MessinaCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy; Valve Center, Poliambulanza Foundation Hospital, Brescia, Italy.
Marco CirilloCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy.
Margherita Dalla TombaCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy.
Gianluca CulluràCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy.
Kiara CoriglianoCardiac Surgery Specialization School, Catholic University of the Sacred Heart, Roma, Italy.
Diego MaffeoValve Center, Poliambulanza Foundation Hospital, Brescia, Italy; Cardiac Surgery Specialization School, Catholic University of the Sacred Heart, Roma, Italy.
Giovanni TroiseCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy; Valve Center, Poliambulanza Foundation Hospital, Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe availability of sutureless prostheses has provided another tool for the treatment of degenerated aortic bioprostheses, mostly those used for aortic root replacement, such as stentless porcine or homograft. However, also sutureless-in-root prosthesis can undergo degeneration, presenting a further surgical challenge. CASE SUMMARY: We present 2 patients facing a degenerated M size Perceval prosthesis, previously implanted in a degenerated Freestyle valve. Both patients received a ballon-expandable valve. One, the younger patient, underwent open-heart surgery for sutureless explantation and then implantation of a new device. The other underwent transcatheter valve-in-valve procedure. DISCUSSION: The treatment of a degenerated sutureless-in-root necessitates re-intervention, with the balloon-expandable devices emerging as a highly promising option also in open-heart setting. TAKE-HOME MESSAGES: Degeneration of Perceval-in-Freestyle bioprostheses can be effectively managed. The choice between surgical and transcatheter implantation should be individualized, considering patient characteristics and anatomical suitability.

Indexed as

aortic replacementaortic valvedegeneratedTAVIvalve-in-valve

Identifiers

PMID41532924
PMCPMC12926010

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Registered trials

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