ArticleJACC. Case reports2026
Managing Pregnancy in the Presence of Rheumatic Heart Disease and Antiphospholipid Syndrome.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundRheumatic heart disease remains a major cause of maternal morbidity and mortality in low- and middle-income countries. The coexistence of severe mitral stenosis (MS) and antiphospholipid syndrome presents an exceptionally high-risk clinical scenario requiring multidisciplinary management. CASE SUMMARY: A 31-year-old woman with severe rheumatic MS and antiphospholipid syndrome presented at 20 weeks of gestation with shortness of breath and palpitations. Echocardiography confirmed severe MS, with a valve area of 0.8 to 0.9 cm DISCUSSION: Pregnancy in women with rheumatic MS and antiphospholipid syndrome demands coordinated care to balance hemodynamic and thrombotic risks while ensuring fetal safety. TAKE-HOME MESSAGE: Timely cardiac intervention, multidisciplinary collaboration, and individualized care enable favorable maternal and fetal outcomes in complex high-risk pregnancies.
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