Evidence map›Paper›PMID 41532689›Full record

ArticleTranslational vision science & technology2026

Assessing the Accuracy of Artificial Intelligence-Generated Clinical Summaries From Ambulatory Glaucoma Subspecialty Clinical Encounters.

Yapei Zhang, Min Shi, In Young Chung, Daniel L Liebman, Laura E Barna, Louis R Pasquale, David S Friedman, Michael V Boland, Lucy Q Shen, Mengyu Wang

Abstract read
In one paragraph

Article in Translational vision science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Comparative evaluation of four large language models (ChatGPT-5, Gemini 2.5 Pro, Claude Sonnet-4, and DeepSeek-R1) for diagnostic and therapeutic decision-making in real-world otolaryngology scenarios.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yapei ZhangDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Min ShiSchepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
In Young ChungDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Daniel L LiebmanDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Laura E BarnaDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Louis R PasqualeEye and Vision Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
David S FriedmanDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Michael V BolandDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Lucy Q ShenDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Mengyu WangHarvard Ophthalmology AI Lab, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.

Funding

VISION RESEARCHP30EY003790 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI Patricia Ann D'Amore · 1985 to 2026
$25.5M
Developing Population-Generalizable Deep Learning Models for Automated Glaucoma ScreeningR01EY036222 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI Mengyu Wang · 2024 to 2026
$2.0M
NEI NIH HHS P30 EY003790NEI NIH HHS R01 EY036222
6 · The paper itself

Abstract

Purpose: The purpose of this study was to evaluate the accuracy of large language model (LLM) LLaMA 2-70B in summarizing glaucoma clinic notes into patient-friendly language and generating educational material. Methods: A random sample of 147 clinic notes from unique patients who visited Glaucoma Service at a tertiary center was analyzed. LLaMA 2 generated paragraph and bullet-point summaries in five subjects: (1) glaucoma diagnosis and type, (2) disease progression, (3) treatment plan, (4) treatment changes, and (5) surgical/laser interventions. Two ophthalmologists reviewed responses for accuracy and categorized them as "correct," "partially correct," or "incorrect." Discrepancies were adjudicated by a glaucoma specialist. A comparison using identical prompts was performed on a subset (n = 50) with ChatGPT-4. Results: LLaMA 2 correctly summarized 97 notes (66%) in paragraph and 103 (70%) in bullet format. Another 44 (30%) and 41 (28%) were partially correct, respectively. Paragraph summaries were more accurate and complete for glaucoma suspects than diagnosed patients (82% vs. 53%, P < 0.001). For targeted clinical questions, LLaMA 2 accurately identified glaucoma diagnosis in 118 notes (80%), disease stability/progression in 129 (88%), treatment plans in 127 (87%), treatment changes in 134 (91%), and surgical/laser interventions in 124 (84%). ChatGPT-4 achieved 46% correct paragraph summaries, 50% correct bullet summaries, and accuracies of 96%, 88%, 64%, 78%, and 82%, respectively, for targeted questions. Conclusions: Although LLaMA 2 is not yet reliable as a standalone clinical tool, it shows promise to improve clinical communication. Translation Relevance: LLMs may enhance patient experience and health literacy by standardizing patient-friendly language in clinical care.

Indexed as

Ambulatory CareArtificial IntelligenceGlaucomaElectronic Health RecordsFemaleGenerative Artificial IntelligenceHumansLarge Language ModelsMalePlain Language Summaries

Identifiers

PMID41532689
PMCPMC12811871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.