ArticleSmall (Weinheim an der Bergstrasse, Germany)2026
Carbon Dot-Based Mechanofluorescent Hydrogel with Tunable Fluorescence for Bioengineering Applications.
Article in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Fluorescent hydrogels are emerging as versatile platforms for tissue engineering and soft robotics due to their ability to transduce mechanical stimuli into optical signals. However, existing systems respond only to large stresses, suffer from fluorescence quenching, and lack bioactive functionalities, limiting their ability to detect and quantify subtle mechanical forces. This study reports on a stimuli-responsive hydrogel with robust mechanics, pH sensitivity, biocompatibility, and pronounced mechano-responsive fluorescence for sensitive, quantitative readout of low mechanical stress. Hydrogels were synthesized from gelatin methacryloyl (GelMA), acrylamide (AM), and polyethylene glycol diacrylate (PEGDA) and infused with carbon-based quantum dots (CQDs) derived from citric acid (GAPC) and cysteine-modified citric acid (GAPCys). Under low compressive forces (250-1250 Pa), the operating range of soft grippers for delicate tissues, hydrogels showed a concentration-dependent linear decrease in photoluminescence, establishing a quantitative correlation between fluorescence intensity and applied stress. The integration of CQDs with tunable hydrogel matrices overcomes fluorescence quenching while maintaining mechanical robustness and bioactivity. These mechanofluorescent hydrogels offer a platform for applications including soft robotic grippers, tissue engineering scaffolds monitoring forces during growth, and implantable sensors for quantitative strain tracking in organs, joints, or vasculature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.