Evidence map›Paper›PMID 41532121›Full record

ArticleBiomedical optics express2026

Automated animal gimbal steering for retinal imaging and stimulation.

Karteek Kunala, Gastón A Ayubi, Joel A Franco, Vinit B Mahajan, Alfredo Dubra

Abstract read
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karteek KunalaByers Eye Institute, Stanford University, Palo Alto, CA 94303, USA.ORCID https://orcid.org/0000-0002-5245-0850
Gastón A AyubiByers Eye Institute, Stanford University, Palo Alto, CA 94303, USA.ORCID https://orcid.org/0000-0002-7790-1793
Joel A FrancoByers Eye Institute, Stanford University, Palo Alto, CA 94303, USA.
Vinit B MahajanByers Eye Institute, Stanford University, Palo Alto, CA 94303, USA.
Alfredo DubraByers Eye Institute, Stanford University, Palo Alto, CA 94303, USA.ORCID https://orcid.org/0000-0002-6506-9020

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Increasing the isoplanatic patch in adaptive optics ophthalmoscopyR01EY032147 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2021 to 2025
$2.4M
Improving rigor and reproducibility in adaptive optics ophthalmoscopyR01EY031360 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2020 to 2023
$2.3M
Low Latency Eye-Motion CompensationR01EY032669 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2021 to 2024
$1.8M
NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY031360NEI NIH HHS R01 EY032147NEI NIH HHS R01 EY032669
6 · The paper itself

Abstract

Here, we propose optomechanical devices for steering anesthetized animals during retinal imaging and/or stimulation with stationary ophthalmoscopes. Simple operating procedures ensure that the entrance pupil of the eye remains centered on the exit pupil of the ophthalmoscope during steering, to avoid vignetting. The devices, built with commercially available manual linear stages and motorized rotating devices, can be used to capture image sequences for tiling, as is often done in microscopy. This automated steering system, demonstrated here in mice, is applicable to other animal species and imaging modalities, as well as explanted eyes. The use of these devices can reduce imaging time and retinal light exposure, both of which are important when using ophthalmoscopes with small fields of view, such as adaptive optics ophthalmoscopes, while also improving animal welfare.

Identifiers

PMID41532121
PMCPMC12795423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.