ArticleBiomedical optics express2026
Long-wavelength oblique back-illumination microscopy for deep
Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Oblique back-illumination microscopy (OBM) is a label-free imaging technique that captures differential forward scattering in reflection mode to generate high-contrast pseudo-transmission images of cells and microvessels. While OBM benefits from multiple light scattering to detect forward-scattered signals, its imaging depth is constrained by tissue scattering between the objective lens and the imaging plane. In this study, we introduce a long-wavelength OBM system operating at 1650 nm-significantly longer than previous implementations-to mitigate scattering effects and extend imaging depth. Compared to a similar system using an 800 nm light source, our 1650 nm OBM achieves markedly deeper
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