Evidence map›Paper›PMID 41532112›Full record

ArticleBiomedical optics express2026

Kohei Umezu, Frank J Brooks, Irina Larina

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kohei UmezuDepartment of Integrative Physiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.ORCID https://orcid.org/0000-0002-4225-9817
Frank J BrooksDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Irina LarinaDepartment of Integrative Physiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.ORCID https://orcid.org/0000-0002-1571-2997

Funding

The Center for Label-free Imagingand Multiscale Biophotonics (CLIMB)P41EB031772 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Stephen A Boppart · 2022 to 2026
$7.6M
In vivo investigation of cilia function in the fallopian tubeR01HD112102 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Irina Larina · 2024 to 2026
$1.8M
In vivo imaging of mammalian fertilizationR01HD116768 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Irina Larina · 2025 to 2026
$1.3M
NIBIB NIH HHS P41 EB031772NICHD NIH HHS R01 HD112102NICHD NIH HHS R01 HD116768
6 · The paper itself

Abstract

Ovulation is preceded by a critical physiological process known as cumulus expansion, during which the cumulus cell layer surrounding the oocyte undergoes structural remodeling. Despite the recognized importance of this process for reproductive success, live quantitative imaging of cumulus expansion has not been previously achieved due to limitations of current imaging technologies for deeply located ovaries. In this study, we employed intravital optical coherence tomography for three-dimensional visualization of mouse follicles containing cumulus-oocyte complexes (COC) within the physiological context of the ovary, both

Identifiers

PMID41532112
PMCPMC12795421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.