Evidence map›Paper›PMID 41532103›Full record

ArticleBiomedical optics express2026

Label-free viability assessment of

Ke Zhang, Qinghao Zhang, Trisha Valerio, Feng Yan, Yan Cui, Ronghao Liu, Xiaoyu Ma, Junyuan Liu, Tri Vu, Chen Wang and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Ke ZhangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0000-0003-3194-2546
Qinghao ZhangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0009-0005-2906-6315
Trisha ValerioStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Feng YanStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0000-0001-9926-7554
Yan CuiStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Ronghao LiuStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Xiaoyu MaDepartment of Electrical and Computer Engineering, University of Massachusetts, Amherst, MA 01003, USA.
Junyuan LiuStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Tri VuStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Chen WangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0000-0003-4645-3227
Bornface MutembeiStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0000-0002-6775-9228
Kaustubh PanditStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0009-0005-9656-4058
Fabricio SilveyraStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Dan DuongStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Clint HostetlerLifeShare of Oklahoma, Oklahoma City, OK 73132, USA.
Ashley MilamLifeShare of Oklahoma, Oklahoma City, OK 73132, USA.
Bradon NaveLifeShare of Oklahoma, Oklahoma City, OK 73132, USA.
Ron SquiresLifeShare of Oklahoma, Oklahoma City, OK 73132, USA.
Zhongxin YuDepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Kar-Ming FungDepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Narendra BattulaDepartment of Surgery, Division of Transplantation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Steven PotterMedStar Georgetown Transplant Institute, Washington, DC 20007, USA.
Chongle PanSchool of Computer Science, University of Oklahoma, Norman, OK 73019, USA.
Wei R ChenStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Yuchen QiuSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Javier JoSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Paulo MartinsDepartment of Surgery, Division of Transplantation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Yuye LingSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0000-0002-4628-7604
Qinggong TangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK 73019, USA.ORCID https://orcid.org/0000-0001-9499-5384

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
Use of 3D Quantitative Optical Methods to Optimize Mebendazole Treatment of Ovarian CancerP20GM135009 · NIGMS · UNIVERSITY OF OKLAHOMA · PI Javier Antonio Jo · 2022 to 2026
$13.6M
Automatic Wide-Field Optical Coherence Tomography for Assessment of Transplant Kidney ViabilityR01DK133717 · NIDDK · UNIVERSITY OF MASSACHUSETTS AMHERST · PI POTTER, STEVEN, TANG, QINGGONG · 2022 to 2025
$2.5M
NCI NIH HHS P30 CA225520NIDDK NIH HHS R01 DK133717NIGMS NIH HHS P20 GM135009
6 · The paper itself

Abstract

Kidney transplantation remains the preferred treatment for patients with end-stage kidney disease. However, the ongoing shortage of donor organs continues to limit the availability of transplant treatments. Existing evaluation methods, such as the kidney donor profile index (KDPI) and pre-transplant donor biopsy (PTDB), have various limitations, including low discriminative power, invasiveness, and sampling errors, which reduce their effectiveness in organ quality assessment and contribute to the risk of unnecessary organ discard. In this study, we explored the dynamic optical coherence tomography (DOCT) as a label-free, non-invasive approach to monitor the viability of

Identifiers

PMID41532103
PMCPMC12795428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.