Evidence map›Paper›PMID 41531798›Full record

ArticleBiochemistry and biophysics reports2026

Pulmonary edema following subarachnoid hemorrhage is associated with impairment of pulmonary vascular endothelial glycocalyx.

Nozomi Sasaki, Yusuke Egashira, Hideshi Okada, Chihiro Takada, Shinomi Sasaibe, Masaki Kumagai, Yoshiki Kuse, Shinsuke Nakamura, Hirofumi Matsubara, Yukiko Enomoto and 4 more

Abstract read
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In one paragraph

Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nozomi SasakiDepartment of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan.
Yusuke EgashiraDepartment of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan.
Hideshi OkadaDepartment of Emergency and Disaster Medicine, Gifu, University Graduate School of Medicine, Gifu, Japan.
Chihiro TakadaDepartment of Emergency and Disaster Medicine, Gifu, University Graduate School of Medicine, Gifu, Japan.
Shinomi SasaibeMolecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.
Masaki KumagaiDepartment of Neurosurgery, Takayama Red Cross Hospital, Gifu, Japan.
Yoshiki KuseMolecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.
Shinsuke NakamuraMolecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.
Hirofumi MatsubaraDepartment of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan.
Yukiko EnomotoDepartment of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan.
Toru IwamaDepartment of Neurosurgery, Gifu Municipal Hospital, Gifu, Japan.
Tsuyoshi IzumoDepartment of Neurosurgery, Gifu University Graduate School of Medicine, Gifu, Japan.
Hideaki HaraMolecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.
Masamitsu ShimazawaMolecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although neurogenic pulmonary edema (NPE) often occurs after aneurysmal subarachnoid hemorrhage (SAH), the mechanism of NPE progression after SAH remains unclear. This study investigates whether pulmonary endothelial glycocalyx (PEG) impairment accompanies NPE after SAH. Accordingly, SAH was induced by endovascular perforation in male mice. The lung tissues of the mice were removed 24 h after SAH induction. The degree of pulmonary edema and lung injury, and the extent of PEG injury were assessed. Water content of lung tissue by the wet/dry method in the SAH group was significantly increased compared to that in the sham group (81.7 % vs. 78.8 %,

Indexed as

Endothelial glycocalyxPulmonary edemaSubarachnoid hemorrhage

Identifiers

PMID41531798
PMCPMC12794039

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.