ArticleClinical case reports2026
New-Onset Complex Partial Seizures Progressing to Intractable Epilepsy in a Young Female With Bifrontal Encephalomalacia and a Remote History of Traumatic Brain Injury.
Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Encephalomalacia, the irreversible loss of brain tissue following injury, is a well-documented cause of post-traumatic epilepsy, typically manifesting within the first year. However, delayed-onset intractable epilepsy in young adults remains underrecognized. We present a case of a young female with bifrontal encephalomalacia secondary to a traumatic brain injury (TBI) six years prior who developed complex partial seizures progressing to intractable epilepsy. Electroencephalography (EEG) confirmed seizure activity predominantly from the right frontal lobe. Despite multiple anti-seizure medications, the patient required intensive care management for refractory status epilepticus. This case highlights the potential for chronic epileptogenesis in TBI survivors, emphasizing the need for long-term vigilance, strict medication adherence, and proactive follow-up to optimize seizure control and prevent recurrence.
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