ArticleFrontiers in public health2025
Association of shift work with metabolic dysfunction-associated fatty liver disease among subway workers.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Circadian and behavioral timing in MASLD: a systematic review of human observational studies.EClinicalMedicine · 2026Article
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Authors and funding
4 authors.
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Abstract
Objective: Inconsistent associations between shift work and metabolic dysfunction-associated fatty liver disease (MAFLD) have been suggested. This study aimed to investigate the association between shift work characteristics and MAFLD in subway workers. Methods: This cross-sectional study was conducted in Wuhan, China, between December 2018 and January 2019, with 9,105 subway workers included after excluding participants with missing data on shift work or ultrasonography, with cancer, or with insufficient data to diagnose MAFLD. All participants were on-duty employees, covering various functional positions such as train drivers, station attendants, maintenance technicians, and administrative staff. Information on demographics, occupational history, and lifestyles was collected through standardized questionnaires. We used logistic regression models to estimate the association of shift work duration and types with MAFLD, and restricted cubic spline regression to examine the potential nonlinear relationship. Mediation analyses were employed to evaluate the potential mediating role of body mass index (BMI). Results: Compared with participants with no shift work, the multivariable-adjusted ORs (95% CIs) for those with ≤3, 3-6, and >6 years of shift work were 0.80 (0.68, 0.94), 1.21 (1.04, 1.41), and 1.60 (1.37, 1.88), respectively. A J-shaped relationship between shift work duration and MAFLD ( Conclusion: Both shift work duration and rotation systems were associated with MAFLD risk in subway workers, with BMI mediating approximately half of these relationships.
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