Evidence map›Paper›PMID 41531463›Full record

ReviewOne health (Amsterdam, Netherlands)2026

An overview of HPAI H5N1 clade 2.3.4.4b and its emerging threat in mainland Australia: Identified knowledge gaps.

Pan Zhang, C Raina MacIntyre

Abstract readReview
In one paragraph

Review in One health (Amsterdam, Netherlands), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pan ZhangBiosecurity Program, Kirby Institute, Faculty of Medicine and Health, University of New South Wales (UNSW), Sydney, Australia.
C Raina MacIntyreBiosecurity Program, Kirby Institute, Faculty of Medicine and Health, University of New South Wales (UNSW), Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The highly pathogenic avian influenza (HPAI) H5N1 virus, particularly clade 2.3.4.4b, is currently causing a panzootic. The threat of its incursion into mainland Australia is escalating, especially following its detection in Antarctica and recently on Australia's sub-Antarctic territory, Heard Island. Comprehensive research on this emerging risk remains limited, partly due to ongoing rapid genomic mutations and evolving epidemiological dynamics. This review provides an in-depth analysis of clade 2.3.4.4b H5N1 and highlights critical knowledge gaps that must be addressed to mitigate the potential threat to mainland Australia.

Indexed as

AntarcticaAustraliaAvian influenzaClade 2.3.4.4bH5N1Heard IslandHPAIIncursion risk

Identifiers

PMID41531463
PMCPMC12794065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.