Evidence map›Paper›PMID 41531218›Full record

ArticleThe Korean journal of internal medicine2026

Prevalence of viral hepatitis A and C in patients with inflammatory bowel disease: a nationwide population-based study in South Korea.

Jin Hwa Park, Sang Hyoung Park, Sang Pyo Lee, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Soorack Ryu, Junwon Go

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Article in The Korean journal of internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jin Hwa ParkDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Korea.
Sang Hyoung ParkDepartment of Gastroenterology and Inflammatory Bowel Disease Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Sang Pyo LeeDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Korea.
Kang Nyeong LeeDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Korea.
Hang Lak LeeDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Korea.
Oh Young LeeDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Korea.
Soorack RyuDepartment of Medicine, College of Medicine, Hanyang University, Seoul, Korea.
Junwon GoBiostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsWe investigated whether patients with inflammatory bowel disease (IBD) in Korea have an increased risk of hepatitis A virus (HAV) and hepatitis C virus (HCV) infections and sought to identify the risk factors for these infections.

methodsWe performed a nationwide population-based study using 2013-2021 data from the Korean National Health Insurance Claims Database. We calculated the incidence rates and standardized incidence ratios (SIRs) of HAV and HCV infections in patients with IBD compared with the overall Korean population.

resultsA total of 43,513 patients were included in this study. A total of 317 cases of HAV were identified in 276,007 perdison- years, while 297 cases of HAV developed in the Korean general population. The SIR of HAV in the patients with IBD was 1.07 (95% confidence interval [CI], 0.96-1.19) and the increase of HAV infection in patients with IBD was not statistically significant. A total of 289 cases of HCV infection were identified in 276,538 person-years, while 242 cases of HCV infection developed in the Korean general population. The SIR of HCV in patients with IBD was 1.19 (95% CI, 1.06-1.34) and the increase of HCV infection in patients with Crohn's disease (SIR, 1.63; 95% CI, 1.31-2.04). Corticosteroid use was identified as a risk factor for HAV and HCV infections in patients with IBD.

conclusionHCV showed an increasing trend in Korean patients with IBD, especially those with Crohn's disease. Corticosteroids use is a risk factor for hepatitis in patients with IBD.

Indexed as

Hepatitis AHepatitis CInflammatory Bowel DiseasesAdolescentAdultAgedDatabases, FactualFemaleHumansIncidenceMaleMiddle AgedPrevalenceRepublic of KoreaRisk AssessmentRisk FactorsCrohn’s diseaseHepatitis AHepatitis CInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID41531218
PMCPMC12800463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.