Evidence map›Paper›PMID 41531216›Full record

ArticleThe Korean journal of internal medicine2026

Risk factors for bleeding from gastric antral vascular ectasia.

Sung Hyun Cho, Jinyoung Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee and 1 more

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Article in The Korean journal of internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Sung Hyun ChoDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jinyoung KimDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hee Kyong NaDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Ji Yong AhnDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jeong Hoon LeeDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kee Wook JungDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Do Hoon KimDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kee Don ChoiDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Ho June SongDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Gin Hyug LeeDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hwoon-Yong JungDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsGastric antral vascular ectasia (GAVE) is a rare but important cause of gastrointestinal (GI) bleeding. The clinical course of GAVE is not well-known, and recurrent bleeding from GAVE is a therapeutic challenge. Therefore, we investigated the clinical course of GAVE and identified the risk factors for bleeding from it.

methodsWe retrospectively reviewed the records of patients diagnosed with GAVE using upper GI endoscopy at Asan Medical Center between January 2004 and December 2019 and evaluated the clinical course and risk factors for bleeding from GAVE.

resultsOf the 348 patients (mean age, 62.3 ± 10.7 years; male, 62%), bleeding from GAVE occurred in 123 (35%) patients during follow-up (median, 17.3 months; interquartile range [IQR], 4.2-46.6). GI bleeding from GAVE was significantly associated with Child-Pugh class B or C liver cirrhosis (odds ratio [OR], 2.55; 95% confidence interval [CI], 1.57-4.16), chronic kidney disease (CKD) (OR, 2.77; 95% CI, 1.52-5.07), use of antithrombotic agents (OR, 2.34; 95% CI, 1.13-4.82), and involvement of the duodenal bulb (OR, 3.21; 95% CI, 1.76-5.86). Rebleeding occurred in 39 of 123 patients (32%), in whom CKD (OR, 2.55; 95% CI, 1.12-5.81) was significantly associated with rebleeding. Endoscopic hemostasis was most commonly performed using argon plasma coagulation, and the median number of endoscopic hemostasis performed was 2 (IQR, 1-3).

conclusionA careful follow-up for bleeding is needed in GAVE patients with liver cirrhosis, CKD, use of antithrombotic agents, and duodenal bulb involvement.

Indexed as

Gastric Antral Vascular EctasiaGastrointestinal HemorrhageAgedFemaleHumansLiver CirrhosisMaleMiddle AgedRecurrenceRetrospective StudiesRisk AssessmentRisk FactorsArgon plasma coagulationEndoscopyGastric antral vascular ectasiaGastrointestinal hemorrhageRisk factors

Identifiers

PMID41531216
PMCPMC12800459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.