Observational studyJournal of orthopaedic surgery and research2026
Early loosening of the femoral stem in cemented segmental prostheses with distal femur replacement (DFR): a multicenter observational study.
Observational study in Journal of orthopaedic surgery and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith the increasing prevalence of knee arthroplasty (TKA), the utilization of segmental prostheses with distal femur replacement (DFR) has expanded, particularly in revision surgeries. Concerns regarding early loosening of cemented femoral stems in these prostheses persist. QUESTIONS/PURPOSES: This study aimed to analyze the rate of early femoral component loosening and associated factors in DFR prostheses. PATIENTS AND
methodsA retrospective multicenter study was conducted, including patients who underwent DFR with cemented stems between 2015 and 2019. Epidemiological variables and outcomes, including femoral component loosening and prosthetic replacement, were analyzed. Statistical methods included survival analysis and subgroup comparisons.
resultsSeventy patients were included, with a femoral component loosening rate of 15.7% within two years. Women exhibited a lower risk of loosening (OR 0.258, 95% CI 0.068-0.098, p = 0.038). Survival analysis showed no significant age-related differences (p = 0.064), but better survival was observed in women (p = 0.045). Previous canal cementation did not significantly affect loosening rates (p = 0.82). Reoperation rates were 24.3%, primarily for mechanical causes.
conclusionsEarly loosening of cemented femoral stems in DFR prostheses is notable, emphasizing the need for enhanced fixation strategies, especially in patients with a history of femoral canal cementation. This study provides valuable insights into optimizing stem fixation systems and addressing concerns related to prosthetic survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.