ArticleParticle and fibre toxicology2026
Inhalation toxicity, pulmonary clearance, and biotransformation of ferric oxide nanoparticles in rats.
Article in Particle and fibre toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Deciphering Pathogenesis of Silica Nanoparticle-Induced Airway Remodeling and Fibrosis: Insights from a Human Patient Cohort and a Murine Model.Nanomaterials (Basel, Switzerland) · 2026Article
- Precision nanomedicine for lung metastatic osteosarcoma: challenges, therapeutic strategies, and perspectives.Materials today. Bio · 2026Review
- Pulmonary toxicity of brake wear particles: effects of composition and surface reactivity.Particle and fibre toxicology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundFerric oxide (Fe
resultsThe toxicity study showed no treatment-related effects, including clinical signs, body weight, hematology, serum biochemistry, or histopathology. Lung burden analysis revealed a clearance half-life of 3.6-3.91 d, with ~ 25% of the initially deposited iron (Fe) retained after 28 d of recovery. At this time point, the retained Fe persisted as particulates biotransformed into fragments of a few nanometers, with a smaller portion present as ionic Fe. The extrapulmonary distribution showed ionic Fe in the liver and spleen, whereas particulate Fe was confined to the lung-associated lymph nodes. This study provides the first inhalation toxicity and biodistribution data for γ-Fe
conclusionsAlthough γ-Fe
Indexed as
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Registered trials
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