ArticleBMC public health2026
Rabies post-exposure prophylaxis in children: adherence to national guidelines in a country at ongoing risk.
Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cost-utility analysis of pre-exposure prophylaxis rabies vaccine in 5-year-old children in Thailand.BMJ global health · 2026Article
- Post-Exposure Rabies Prophylaxis in Children: Real-World Practices From an 11-Year Retrospective Study in Türkiye.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRabies is a preventable but fatal zoonotic disease, and children account for a large share of exposures worldwide. Türkiye is regarded as rabies-endemic because of ongoing circulation in terrestrial animals, particularly dogs, although human cases are rare because of effective surveillance and post-exposure prophylaxis. Adherence to post-exposure prophylaxis guidelines is crucial for prevention. This study evaluated the appropriateness of initial rabies post-exposure prophylaxis administered to pediatric patients according to the 2019 Turkish Ministry of Health guideline.
methodsThis retrospective descriptive study included children under 18 years who presented to the emergency department of a tertiary hospital with suspected rabies exposure and were evaluated in the pediatric infectious diseases clinic between January and December 2024. Demographics, animal type, exposure category, and administration of rabies vaccine and immunoglobulin were recorded. Compliance was determined by comparing actual management with guideline recommendations.
resultsA total of 523 patients (median age 8 years; 56.4% male) were evaluated. Cats were the main exposure source (71.1%), and 84.1% were Category II. Although all patients received the rabies vaccine, 71.3% of these administrations were deemed unnecessary based on guideline criteria, mostly due to minor, provoked, non-bleeding cat scratches. Of 41 patients requiring rabies immunoglobulin, only 6 (14.6%) received it appropriately. Full compliance was achieved in 21.9% of cases. Inappropriate vaccination predominated in cat exposures, while immunoglobulin underuse was common in dog bites (p < 0.001).
conclusionsMajor inconsistencies exist between practice and national rabies post-exposure prophylaxis guidelines in children. Over-vaccination and inadequate immunoglobulin use highlight the need for standardized risk assessment and ongoing professional education.
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